Record in detail


General Info

  • lamp_id:L01A000694
  • Name:BMNH5_BOMVA
  • FullName:Bombinin-H5
  • Source:Bombina variegata
  • Mass:1918.4 Da
  • Sequence Length:20 aa
  • Isoelectric Point:10.8
  • Activity:Antibacterial
  • Sequence
        IIGPVLGLVGSALGGLLKKI
  • Function:Has antimicrobial and hemolytic activities.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000694    From 1 To 20 E-value: 0.0002 Score: 36.2
        IIGPVLGLVGSALGGLLKKI
  • 2. L13A019127    From 1 To 20 E-value: 0.0002 Score: 35.8
        IIGPVLGLVGSALGGLLKKI
  • 3. L02A000055    From 1 To 20 E-value: 0.0002 Score: 35.8
        IIGPVLGMVGSALGGLLKKI
  • 4. L01A000692    From 1 To 20 E-value: 0.0003 Score: 35.4
        IIGPVLGMVGSALGGLLKKI
  • 5. L02A000056    From 1 To 20 E-value: 0.0004 Score: 35
        LIGPVLGLVGSALGGLLKKI

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

Activity

  •   Antibacterial Activities
  •   1  Target:  E.coli D21  MIC:  9.59 μg/ml  (4.99896 μM)  
  •   2  Target:  S.aureus Cowan 1  MIC:  5.76 μg/ml  (3.0025 μM)  
  •   3  Target:  E. coli  MIC:  8.44096 μg/ml  (4.4 μM)  
  •   4  Target:  S. aureus  MIC:  9.01648 μg/ml  (4.7 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Barra D.,Kreil G.,Simmaco M.,Mignogna G.,
  •   Title:Antibacterial and haemolytic peptides containing D-alloisoleucine from the skin of Bombina variegata.
  •   Journal:EMBO J., 1993, 12, 4829-4832  [MEDLINE:94038967]

Comments

  •   Comments

  •     No comments found on LAMP database



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