Record in detail
General Info
- lamp_id:L01A000698
- Name:ALLIU_ALLSA
- FullName:Alliumin
- Source:Allium sativum
- Mass:1013.1 Da
- Sequence Length:10 aa
- Isoelectric Point:3.49
- Activity:Antibacterial, Antifungal
- Sequence
DDFLCAGGCL - Function:Has antifungal activity against M.arachidicola with an IC(50) of 1.3uM, but not against F.oxysporum. Has antibacterial activity against the Gram-negative bacterium P.fluorescens. No antibacterial activity against the Gram-positive bacteria B.subtilis, B.cereus and B.megaterium, or against the Gram-negative bacterium E.coli. Has antiproliferative activity towards L1210 leukemia cells with an IC(50) of 8.33 uM, but lacks antiproliferative activity towards HepG2 hepatoma cells. Lacks mitogenic towards murine splenocytes. Lacks ribonuclease activity towards yeast tRNA and protease activity towards casein.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ654
- 2 Database:DBAASP 1681
- 3 Database:dbAMP dbAMP_01001
- 4 Database:DRAMP DRAMP01009
- 5 Database:SATPdb satpdb23553
- 6 Database:Uniprot P84796
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000698 From 1 To 10 E-value: 0.57 Score: 23.5
DDFLCAGGCL - 2. L13A019748 From 1 To 9 E-value: 1.5 Score: 21.9
DDFLCAGGC
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Mycosphaerella arachidicola IC50: 1.3 μg/ml (1.28319 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Ng T.B.,Xia L.,
- Title:Isolation of alliumin, a novel protein with antimicrobial and antiproliferative activities from multiple-cloved garlic bulbs.
- Journal:Peptides, 2005, 26, 177-183 [PubMed:15629528]
Comments
- Comments
No comments found on LAMP database