Record in detail


General Info

  • lamp_id:L01A000711
  • Name:AMP_IMPBA
  • FullName:Antimicrobial peptides
  • Source:Impatiens balsamina
  • Mass:2485.9 Da
  • Sequence Length:20 aa
  • Isoelectric Point:9.72
  • Activity:Antibacterial, antifungal
  • Sequence
        QWGRRCCGWGPGRRYCVRWC
  • Function:Plays a role in the defense of the germinating seed against micro-organisms, by inhibiting the growth of a range of filamentous fungi and bacteria, especially Gram-positive bacteria. Not cytotoxic for cultured human cells and are the smallest known plant-derived antimicrobial peptides. Peptide IB-AMP4 has a higher antifungal activity than IB-AMP1.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000711    From 1 To 20 E-value: 0.000002 Score: 42.7
        QWGRRCCGWGPGRRYCVRWC
  • 2. L13A025629    From 1 To 20 E-value: 0.000004 Score: 41.6
        EWGRRCCGWGPGRRYCVRWC
  • 3. L11A001376    From 2 To 20 E-value: 0.000008 Score: 40.4
        WGRRCCGWGPGRRYCVRWC
  • 4. L01A000714    From 1 To 20 E-value: 0.00001 Score: 40
        QWGRRCCGWGPGRRYCRRWC
  • 5. L13A013121    From 1 To 20 E-value: 0.00002 Score: 39.3
        EWGRRCCGWGPGRRYCRRWC

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Alternaria longipes  MIC:  3 μg/ml  (1.20681 μM)  
  •   2  Target:  Botrytis cinerea  MIC:  12 μg/ml  (4.82723 μM)  
  •   3  Target:  Cladosporium sphaerospermum  MIC:  1 μg/ml  (0.402269 μM)  
  •   4  Target:  F. culmorum  MIC:  1 μg/ml  (0.402269 μM)  
  •   5  Target:  Penicillium digitatum  MIC:  3 μg/ml  (1.20681 μM)  
  •   6  Target:  T. viride  MIC:  6 μg/ml  (2.41361 μM)  
  •   7  Target:  V. alboatrum  MIC:  3 μg/ml  (1.20681 μM)  
  •   8  Target:  Alternaria longipes  MIC:  50 μg/ml  (20.1134 μM)  
  •   9  Target:  Botrytis cinerea  MIC:  200 μg/ml  (80.4538 μM)  
  •   10  Target:  Cladosporium sphaerospermum  MIC:  50 μg/ml  (20.1134 μM)  
  •   11  Target:  F. culmorum  MIC:  50 μg/ml  (20.1134 μM)  
  •   12  Target:  Penicillium digitatum  MIC:  200 μg/ml  (80.4538 μM)  
  •   13  Target:  T. viride  MIC:  200 μg/ml  (80.4538 μM)  
  •   14  Target:  V. Alboatrum  MIC:  200 μg/ml  (80.4538 μM)  
  •   15  Target:  ]Antibacterial[Bacillus subtilis  MIC:  10 μg/ml  (4.02269 μM)  
  •   16  Target:  Micrococcus luteus  MIC:  10 μg/ml  (4.02269 μM)  
  •   17  Target:  Staphylococcus aureus  MIC:  30 μg/ml  (12.0681 μM)  
  •   18  Target:  Streptococcus faecalis  MIC:  6 μg/ml  (2.41361 μM)  
  •   19  Target:  Erwinia amylovora Escherichia coli  MIC:  500 μg/ml  (201.134 μM)  
  •   20  Target:  Proteus vulgaris  MIC:  500 μg/ml  (201.134 μM)  
  •   21  Target:  Pseudomonas solanacearum  MIC:  500 μg/ml  (201.134 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Evans I.J.,Cammue B.P.A.,Attenborough S.,Acland D.P.,Tailor R.H.,
  •   Title:A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.
  •   Journal:J. Biol. Chem., 1997, 272, 24480-24487  [MEDLINE:97450977]
  •   [2]  Thornton J.M.,Rees S.B.,Osborn R.W.,Patel S.U.,
  •   Title:Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1).
  •   Journal:Biochemistry, 1998, 37, 983-990  [MEDLINE:98128575]

Comments

  •   Comments

    •     No comments found on LAMP database



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