Record in detail
General Info
- lamp_id:L01A000712
- Name:AMP_IMPBA
- FullName:Antimicrobial peptides
- Source:Impatiens balsamina
- Mass:2549 Da
- Sequence Length:20 aa
- Isoelectric Point:10.07
- Activity:Antibacterial, antifungal
- Sequence
QYGRRCCNWGPGRRYCKRWC - Function:Plays a role in the defense of the germinating seed against micro-organisms, by inhibiting the growth of a range of filamentous fungi and bacteria, especially Gram-positive bacteria. Not cytotoxic for cultured human cells and are the smallest known plant-derived antimicrobial peptides. Peptide IB-AMP4 has a higher antifungal activity than IB-AMP1.
Cross-Linking
- Cross-linking
- 1 Database:APD 914
- 2 Database:CAMP CAMPSQ668
- 3 Database:dbAMP dbAMP_10328
- 4 Database:DRAMP DRAMP00995
- 5 Database:SATPdb satpdb15211
- 6 Database:Uniprot O24006
- 7 Database:PHY PHYT00266
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000712 From 1 To 20 E-value: 0.000001 Score: 43.5
QYGRRCCNWGPGRRYCKRWC - 2. L11A001380 From 2 To 20 E-value: 0.000004 Score: 41.6
YGRRCCNWGPGRRYCKRWC - 3. L01A000714 From 1 To 20 E-value: 0.00004 Score: 38.5
QWGRRCCGWGPGRRYCRRWC - 4. L01A000711 From 1 To 20 E-value: 0.00006 Score: 37.7
QWGRRCCGWGPGRRYCVRWC - 5. L13A013121 From 1 To 20 E-value: 0.00007 Score: 37.4
EWGRRCCGWGPGRRYCRRWC
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Alternaria longipes MIC: 12 μg/ml (4.70773 μM)
- 2 Target: Botrytis cinerea MIC: 25 μg/ml (9.80777 μM)
- 3 Target: Cladosporium sphaerospermum MIC: 6 μg/ml (2.35386 μM)
- 4 Target: F. culmorum MIC: 6 μg/ml (2.35386 μM)
- 5 Target: Penicillium digitatum MIC: 6 μg/ml (2.35386 μM)
- 6 Target: T. viride MIC: 12 μg/ml (4.70773 μM)
- 7 Target: V. alboatrum MIC: 12 μg/ml (4.70773 μM)
- 8 Target: Alternaria longipes MIC: 200 μg/ml (78.4621 μM)
- 9 Target: Botrytis cinerea MIC: 200 μg/ml (78.4621 μM)
- 10 Target: Cladosporium sphaerospermum MIC: 200 μg/ml (78.4621 μM)
- 11 Target: F. culmorum MIC: 200 μg/ml (78.4621 μM)
- 12 Target: Penicillium digitatum MIC: 200 μg/ml (78.4621 μM)
- 13 Target: T. viride MIC: 200 μg/ml (78.4621 μM)
- 14 Target: V. Alboatrum MIC: 200 μg/ml (78.4621 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Evans I.J.,Cammue B.P.A.,Attenborough S.,Acland D.P.,Tailor R.H.,
- Title:A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.
- Journal:J. Biol. Chem., 1997, 272, 24480-24487 [MEDLINE:97450977]
- [2] Thornton J.M.,Rees S.B.,Osborn R.W.,Patel S.U.,
- Title:Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1).
- Journal:Biochemistry, 1998, 37, 983-990 [MEDLINE:98128575]
Comments
- Comments
No comments found on LAMP database