Record in detail

lamp_id:L01A001794
Name:ES1B_RANES
FullName:Esculentin-1B
Source:Rana esculenta
Mass:4802.8 Da
Sequence Length:46 aa
Isoelectric Point:10.34
Activity:Antibacterial
Sequence
GIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
Function:Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.

Top similar AMPs on LAMP
1. L03A000115 From 39 To 84 E-value: 2e-20 Score: 89.4
GIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
2. L01A001794 From 1 To 46 E-value: 5e-20 Score: 88.2
GIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
3. L12A04132| From 25 To 70 E-value: 5e-20 Score: 88.2
GIFSKLAGKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
4. L12A04130| From 25 To 70 E-value: 8e-20 Score: 87.4
GIFSKLAGKKIKNLLISGLKNIGKEVGMDVVRTGIDIAGCKIKGEC
5. L12A04123| From 25 To 70 E-value: 9e-20 Score: 87.4
GIFSKLAGKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC

Antibacterial Activities
1 Target: E.coli D21 MIC: 0.96 μg/ml (0.199883 μM)
2 Target: B megaterium BmII MIC: 0.48 μg/ml (0.0999417 μM)
3 Target: S. aureus cowan I MIC: 1.92 μg/ml (0.399767 μM)
4 Target: P.aeruginosa ATCC15692 MIC: 3.36 μg/ml (0.699592 μM)
5 Target: C.ablicans MIC: 2.4 μg/ml (0.499709 μM)
6 Target: S.cerevisiae MIC: 4.32 μg/ml (0.899475 μM)

Reference
[1] Bossa F.,Barra D.,Mignogna G.,Simmaco M.,
Title:Antimicrobial peptides from skin secretions of Rana esculenta. Molecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides.
Journal:J. Biol. Chem., 1994, 269, 11956-11961 [MEDLINE:94216303]