Record in detail


General Info

  • lamp_id:L01A002353
  • Name:CR16_LITCH
  • FullName:Caerin-1.6
  • Source:Litoria chloris
  • Mass:2481 Da
  • Sequence Length:24 aa
  • Isoelectric Point:9.54
  • Activity:Antibacterial,Anticancer
  • Sequence
        GLFSVLGAVAKHVLPHVVPVIAEK
  • Function:Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes. Each caerin displays a different antimicrobial specificity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000528    From 1 To 24 E-value: 0.0000001 Score: 47.4
        GLFSVLGAVAKHVLPHVVPVIAEK
  • 2. L01A002353    From 1 To 24 E-value: 0.0000001 Score: 47.4
        GLFSVLGAVAKHVLPHVVPVIAEK
  • 3. L01A000103    From 1 To 24 E-value: 0.0000003 Score: 45.4
        GLFSVLGSVAKHLLPHVVPVIAEK
  • 4. L13A015909    From 1 To 24 E-value: 0.0000004 Score: 45.4
        GLFSVLGSVAKHLLPHVVPVIAEK
  • 5. L01A000031    From 1 To 24 E-value: 0.0000008 Score: 44.3
        GLLSVLGSVAKHVLPHVVPVIAEK

Structure

  •   Domains
  •   1  Name:Caerin_1    Interpro Link:IPR010000
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  47.8089 μg/ml  (19.27 μM)  
  •   2  Target:  S. aureus  MIC:  5.73111 μg/ml  (2.31 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Tyler M.J.,Wallace J.C.,Bowie J.H.,Currie G.J.,Steinborner S.T.,
  •   Title:New antibiotic caerin 1 peptides from the skin secretion of the Australian tree frog Litoria chloris. Comparison of the activities of the caerin 1 peptides from the genus Litoria.
  •   Journal:J. Pept. Res., 1998, 51, 121-126  [MEDLINE:98175802]

Comments

  •   Comments

    •     No comments found on LAMP database



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