Record in detail
General Info
- lamp_id:L01A002366
- Name:CR21_LITSP
- FullName:Caerin-2.1
- Source:Litoria splendida
- Mass:2393.8 Da
- Sequence Length:25 aa
- Isoelectric Point:10.79
- Activity:Antibacterial
- Sequence
GLVSSIGRALGGLLADVVKSKGQPA - Function:Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes. Each caerin displays a different antimicrobial specificity.
Cross-Linking
- Cross-linking
- 1 Database:APD 249
- 2 Database:CAMP CAMPSQ721
- 3 Database:DBAASP 3918
- 4 Database:dbAMP dbAMP_03789
- 5 Database:DRAMP DRAMP01562
- 6 Database:SATPdb satpdb15585
- 7 Database:Uniprot P56233
- 8 Database:AMD CR21_LITSP
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A002366 From 1 To 25 E-value: 0.00000005 Score: 48.1
GLVSSIGRALGGLLADVVKSKGQPA - 2. L03A000047 From 1 To 25 E-value: 0.0000001 Score: 47
GLVSSIGKALGGLLADVVKSKGQPA - 3. L13A016574 From 1 To 24 E-value: 0.0000002 Score: 46.6
LVSSIGRALGGLLADVVKSKGQPA - 4. L01A002830 From 1 To 25 E-value: 0.0000002 Score: 45.8
GLVSSIGRALGGLLADVVKSKEQPA - 5. L13A023052 From 1 To 25 E-value: 0.0000004 Score: 45.1
GLVSSIGKVLGGLLADVVKSKGQPA
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Pasteurella multocida MIC: 25 μg/ml (10.4436 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Tyler M.J.,Wallace J.C.,Bowie J.H.,Waugh R.J.,Stone D.J.M.,
- Title:Peptides from Australian frogs. Structures of the caerins and caeridin 1 from Litoria splendida.
- Journal:J. Chem. Soc. Perkin Trans. I, 1992, 1, 3173-3178 [:]
Comments
- Comments
No comments found on LAMP database