Record in detail


General Info

  • lamp_id:L01A002367
  • Name:CR15_LITCE
  • FullName:Caerin-1.5
  • Source:Litoria caerulea
  • Mass:2613.2 Da
  • Sequence Length:25 aa
  • Isoelectric Point:7.81
  • Activity:Antibacterial,Anticancer
  • Sequence
        GLLSVLGSVVKHVIPHVVPVIAEHL
  • Function:Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes. Each caerin displays a different antimicrobial specificity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A06177|    From 50 To 74 E-value: 0.0000001 Score: 47
        GLLSVLGSVAKHVLPHVVPVIAEHL
  • 2. L12A06176|    From 50 To 74 E-value: 0.0000001 Score: 46.6
        GLLSVLGSVAKHVLPHVVPVIAEHL
  • 3. L01A002367    From 1 To 25 E-value: 0.0000001 Score: 46.6
        GLLSVLGSVVKHVIPHVVPVIAEHL
  • 4. L01A000530    From 1 To 25 E-value: 0.0000006 Score: 44.7
        GLLSVLGSVAKHVLPHVVPVIAEHL
  • 5. L01A002368    From 1 To 25 E-value: 0.000001 Score: 43.5
        GLLSVLGSVAQHVLPHVVPVIAEHL

Structure

  •   Domains
  •   1  Name:Caerin_1    Interpro Link:IPR010000
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S. aureus  MIC:  25.0345 μg/ml  (9.58 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Tyler M.J.,Wallace J.C.,Bowie J.H.,Waugh R.J.,Stone D.J.M.,
  •   Title:Peptides from Australian frogs. The structures of the caerins from Litoria caerula.
  •   Journal:J. Chem. Res., 1993, 138, 910-936  [:]

Comments

  •   Comments

  •     No comments found on LAMP database



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