Record in detail


General Info

  • lamp_id:L01A002368
  • Name:CR13_LITCE
  • FullName:Caerin-1.3
  • Source:Litoria caerulea
  • Mass:2585.1 Da
  • Sequence Length:25 aa
  • Isoelectric Point:6.79
  • Activity:Antibacterial,Anticancer
  • Sequence
        GLLSVLGSVAQHVLPHVVPVIAEHL
  • Function:Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes. Each caerin displays a different antimicrobial specificity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A06177|    From 50 To 74 E-value: 0.00000004 Score: 48.5
        GLLSVLGSVAKHVLPHVVPVIAEHL
  • 2. L12A06176|    From 50 To 74 E-value: 0.00000005 Score: 48.1
        GLLSVLGSVAKHVLPHVVPVIAEHL
  • 3. L01A002368    From 1 To 25 E-value: 0.00000008 Score: 47.4
        GLLSVLGSVAQHVLPHVVPVIAEHL
  • 4. L01A000530    From 1 To 25 E-value: 0.0000002 Score: 46.2
        GLLSVLGSVAKHVLPHVVPVIAEHL
  • 5. L13A010626    From 1 To 24 E-value: 0.0000005 Score: 45.1
        GLLSVLGSVAKHVLPHVVPVIAEH

Structure

  •   Domains
  •   1  Name:Caerin_1    Interpro Link:IPR010000
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S. aureus  MIC:  5.94573 μg/ml  (2.3 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Tyler M.J.,Wallace J.C.,Bowie J.H.,Waugh R.J.,Stone D.J.M.,
  •   Title:Peptides from Australian frogs. The structures of the caerins from Litoria caerula.
  •   Journal:J. Chem. Res., 1993, 138, 910-936  [:]

Comments

  •   Comments

  •     No comments found on LAMP database



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