Record in detail

General Info

lamp_id:L01A002376
Name:MCU21_LITGE
FullName:Maculatin-2.1
Source:Litoria genimaculata
Mass:1879.2 Da
Sequence Length:18 aa
Isoelectric Point:9.53
Activity:Antibacterial,Anticancer
Sequence
GFVDFLKKVAGTIANVVT
Function:Shows antibacterial activity against B.cereus, L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis.

Cross-Linking

Cross-linking
1 Database:APD 262
2 Database:CAMP CAMPSQ2819
3 Database:DBAASP 3896
4 Database:dbAMP dbAMP_02703
5 Database:DRAMP DRAMP01368
6 Database:SATPdb satpdb17364
7 Database:Uniprot P82068
8 Database:AMD MAC21_LITGE

Top similar AMPs

Top similar AMPs on LAMP
1. L01A002376 From 1 To 18 E-value: 0.0001 Score: 36.6
GFVDFLKKVAGTIANVVT
2. L01A000677 From 1 To 17 E-value: 2.8 Score: 21.9
GFVDLAKKVVGGIRNAL
3. L01A000676 From 1 To 15 E-value: 3.7 Score: 21.6
GIVDFAKKVVGGIRN
4. L12A06191| From 50 To 66 E-value: 5.1 Score: 21.2
GLFDIVKKIAGHIAGSI
5. L01A000680 From 1 To 17 E-value: 7.3 Score: 20.8
GIVDFAKGVLGKIKNVL

Structure

Domains
1 Name:Aurein_antimicrobial_peptide Interpro Link:IPR013157

Structures

Activity

Antibacterial Activities
1 Target: S. aureus MIC: 100.067 μg/ml (53.25 μM)

Toxicity

Toxicity

Reference

Reference
[1] Tyler M.J.,Bowie J.H.,Steinborner S.T.,Waugh R.J.,Rozek T.,
Title:The maculatin peptides from the skin glands of the tree frog Litoria genimaculata. A comparison of the structures and antibacterial activities of maculatin 1.1 and caerin 1.1.
Journal:J. Pept. Sci., 1998, 4, 111-115 [MEDLINE:98281937]

Comments

Comments