Record in detail
General Info
- lamp_id:L01A002472
- Name:LYC3_LYCSI
- FullName:M-lycotoxin-Ls2a
- Source:Lycosa singoriensis
- Mass:3149.9 Da
- Sequence Length:26 aa
- Isoelectric Point:11.02
- Activity:Antibacterial, Antifungal
- Sequence
KIKWFKTMKSLAKFLAKEQMKKHLGE - Function:Forms pore that permeabilize the cell membrane. Promotes efflux of calcium from synaptosomes, causes hemolysis, and dissipates voltage gradients across muscle membrane. Potently inhibits the growth of bacteria and yeast. May function both in the prey capture strategy as well as protection from infectious organisms arising from prey ingestion (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1323
- 2 Database:dbAMP dbAMP_05091
- 3 Database:DRAMP DRAMP03252
- 4 Database:Uniprot P0C2U8
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A002472 From 1 To 26 E-value: 0.000000004 Score: 51.6
KIKWFKTMKSLAKFLAKEQMKKHLGE - 2. L01A000521 From 1 To 25 E-value: 0.00000005 Score: 48.5
KIKWFKTMKSIAKFIAKEQMKKHLG - 3. L13A022267 From 4 To 24 E-value: 0.0004 Score: 35.4
WFKAMKSIAKFIAKEKLKEHL
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Galkina T.G.,Anisimova V.E.,Egorov T.A.,Olsen J.V.,Budnik B.A.,
- Title:De novo sequencing of antimicrobial peptides isolated from the venom glands of the wolf spider Lycosa singoriensis.
- Journal:J. Mass Spectrom., 2004, 39, 193-201 [PubMed:14991689]
Comments
- Comments
No comments found on LAMP database