Record in detail
General Info
- lamp_id:L01A002501
- Name:DEFB2_MOUSE
- FullName:Beta-defensin 2
- Source:Mus musculus
- Mass:5546.4 Da
- Sequence Length:51 aa
- Isoelectric Point:8.38
- Activity:Antimicrobial
- Sequence
AVGSLKSIGYEAELDHCHTNGGYCVRAICPPSARRPGSCFPEKNPCCKYMK - Function:Has bactericidal activity (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1346
- 2 Database:dbAMP dbAMP_00713
- 3 Database:DRAMP DRAMP03367
- 4 Database:Uniprot P82020
- 5 Database:DEF DEF130
- 6 Database:RAP RAPD0171
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000282 From 21 To 71 E-value: 3e-26 Score: 108
AVGSLKSIGYEAELDHCHTNGGYCVRAICPPSARRPGSCFPEKNPCCKYMK - 2. L01A002501 From 1 To 51 E-value: 6e-26 Score: 107
AVGSLKSIGYEAELDHCHTNGGYCVRAICPPSARRPGSCFPEKNPCCKYMK - 3. L12A00855| From 1 To 34 E-value: 8e-16 Score: 73.9
CHTNGGYCVRAICPPSARRPGSCFPEKNPCCKYM - 4. L05ADEF162 From 21 To 71 E-value: 0.0000001 Score: 46.6
AVGDLKHLILKAQLARCYKFGGFCYNSMCPPHTKFIGNCHPDHLHCCINMK - 5. L05ADEF161 From 21 To 71 E-value: 0.0000004 Score: 45.4
AVGDLKHLILKAQLTRCYKFGGFCHYNICPGNSRFMSNCHPENLRCCKNIK
Structure
- Domains
- 1 Name:Defensin_beta-typ Interpro Link:IPR001855
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Dorin J.R.,Davidson D.J.,Morrison G.M.,
- Title:A novel mouse beta defensin, Defb2, which is upregulated in the airways by lipopolysaccharide.
- Journal:FEBS Lett., 1999, 442, 112-116 [MEDLINE:99120490]
Comments
- Comments
No comments found on LAMP database