Record in detail
General Info
- lamp_id:L01A002536
- Name:D106A_HUMAN
- FullName:Beta-defensin 106
- Source:Homo sapiens
- Mass:5038.9 Da
- Sequence Length:45 aa
- Isoelectric Point:8.29
- Activity:Antimicrobial
- Sequence
FFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID - Function:Has antibacterial activity.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1375
- 2 Database:dbAMP dbAMP_01635
- 3 Database:DRAMP DRAMP02676
- 4 Database:SATPdb satpdb22998
- 5 Database:Uniprot Q8N104
- 6 Database:DEF DEF206
- 7 Database:RAP RAPD0142
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L05A00DEF7 From 21 To 65 E-value: 3e-21 Score: 92.4
FFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID - 2. L01A002536 From 1 To 45 E-value: 1e-20 Score: 90.5
FFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID - 3. L12A01333| From 2 To 46 E-value: 4e-20 Score: 88.6
FFDEKCGKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID - 4. L01A003437 From 1 To 45 E-value: 4e-20 Score: 88.2
FFDEKCGKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID - 5. L12A01636| From 1 To 45 E-value: 4e-20 Score: 88.2
FFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPSGSIID
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Jia H.P.,Walters J.D.,Bartlett J.A.,Mitros J.P.,Schutte B.C.,
- Title:Discovery of five conserved beta-defensin gene clusters using a computational search strategy.
- Journal:Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 2129-2133 [MEDLINE:21843921]
- [2] Tomita T.,Fukuhara S.,Makita R.,Nagase T.,Yamaguchi Y.,
- Title:Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.
- Journal:J. Immunol., 2002, 169, 2516-2523 [MEDLINE:22181517]
- [3] Dorin J.R.,Rolfe M.,Semple C.A.M.,
- Title:Duplication and selection in the evolution of primate beta-defensin genes.
- Journal:Genome Biol., 2003, 4, 0-0 [MEDLINE:22619651]
- [4] Wu R.,Zhao Y.H.,Chen Y.,Kao C.Y.,
- Title:ORFeome-based search of airway epithelial cell-specific novel human beta-defensin genes.
- Journal:Am. J. Respir. Cell Mol. Biol., 2003, 29, 71-80 [MEDLINE:22705149]
- [5]
- Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
- Journal:Genome Res., 2004, 14, 2121-2127 [PubMed:15489334]
Comments
- Comments
No comments found on LAMP database