Record in detail


General Info

  • lamp_id:L01A002667
  • Name:PG4_PIG
  • FullName:Protegrin-4
  • Source:Sus scrofa
  • Mass:2105.5 Da
  • Sequence Length:18 aa
  • Isoelectric Point:9.08
  • Activity:Antimicrobial
  • Sequence
        RGGRLCYCRGWICFCVGR
  • Function:Microbicidal activity (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002667    From 1 To 18 E-value: 0.00003 Score: 38.5
        RGGRLCYCRGWICFCVGR
  • 2. L01A002668    From 1 To 18 E-value: 0.021 Score: 28.9
        RGGRLCYCRPRFCVCVGR
  • 3. L03A000324    From 1 To 18 E-value: 0.025 Score: 28.9
        RGGRLCYCRPRFCVCVGR
  • 4. L12A10434|    From 1 To 18 E-value: 0.035 Score: 28.5
        RGGRLCYCRRRFCVCVGR
  • 5. L01A002867    From 1 To 18 E-value: 0.035 Score: 28.5
        RGGRLCYCRRRFCVCVGR

Structure

  •   Domains
  •   1  Name:Cathelicidin    Interpro Link:IPR001894
  •   2  Name:Cathelicidin_CS    Interpro Link:IPR018216
  •   Structures

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lehrer R.I.,Liu L.,Zhao C.,
  •   Title:Identification of a new member of the protegrin family by cDNA cloning.
  •   Journal:FEBS Lett., 1994, 346, 285-288  [MEDLINE:94283613]
  •   [2]  Aumelas A.,Brutscher B.,Strub M.-P.,Sanchez J.F.,Yang Y.,
  •   Title:NMR structure of the cathelin-like domain of the protegrin-3 precursor.
  •   Journal:Biochemistry, 2003, 42, 4669-4680  [PubMed:12705830]

Comments

  •   Comments

  •     No comments found on LAMP database



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