Record in detail

lamp_id:L01A002677
Name:CRYPT_CRYDU
FullName:Cryptonin
Source:Cryptotympana dubia
Mass:2704.4 Da
Sequence Length:24 aa
Isoelectric Point:12.53
Activity:Antibacterial, Antifungal
Sequence
GLLNGLALRLGKRALKKIIKRLCR
Function:Antimicrobial peptide, active against the Gram-negative bacterium E.coli K12-594 (MIC=3.12 ug/ml), the Gram-positive bacteria B.subtilis KCTC 3086 (MIC=3.12 ug/ml), S.aureus KCTC 1928 (MIC=25 ug/ml) and M.luteus KCTC 3063 (MIC=1.56 ug/ml), the antibiotic resistant bacteria methicilin-resistant S.aureus (MRSA) (MIC=25 ug/ml) and vancomycin-resistant Enterococci (VRE) (MIC=25 ug/ml), and the fungi C.albicans KCTC 7965 (MIC=50 ug/ml) and C.tropicalis KCTC 1925 (MIC=3.12 ug/ml). Has very low hemolytic activity on rat erythrocytes.

Top similar AMPs on LAMP
1. L01A002677 From 1 To 24 E-value: 0.0000008 Score: 44.3
GLLNGLALRLGKRALKKIIKRLCR

Antibacterial Activities
1 Target: E.coli K12-594 MIC: 3.12 μg/ml (1.15368 μM)
2 Target: B.subtilis KCTC 3086 MIC: 3.12 μg/ml (1.15368 μM)
3 Target: S.aureus KCTC 1928 MIC: 25 μg/ml (9.24419 μM)
4 Target: M.luteus KCTC 3063 MIC: 1.56 μg/ml (0.576838 μM)
5 Target: vancomycin-resistant Enterococci VRE MIC: 25 μg/ml (9.24419 μM)
6 Target: C.albicans KCTC 7965 MIC: 50 μg/ml (18.4884 μM)
7 Target: C.tropicalis KCTC 1925 MIC: 3.12 μg/ml (1.15368 μM)

Reference
[1] Oh H.-W.,Hur J.H.,Suh E.Y.,Leem J.Y.,Park D.-S.,
Title:Isolation and functional analysis of a 24-residue linear alpha-helical antimicrobial peptide from Korean blackish cicada, Cryptotympana dubia (Homoptera).
Journal:Arch. Insect Biochem. Physiol., 2007, 66, 204-213 [PubMed:18000874]