Record in detail
General Info
- lamp_id:L01A002713
- Name:DEF1_RABIT
- FullName:Corticostatin 1
- Source:Oryctolagus cuniculus
- Mass:4003.6 Da
- Sequence Length:34 aa
- Isoelectric Point:10.19
- Activity:Antimicrobial
- Sequence
GICACRRRFCPNSERFSGYCRVNGARYVRCCSRR - Function:Microbicidal activity and inhibits corticotropin (ACTH) stimulated corticosterone production.
Cross-Linking
- Cross-linking
- 1 Database:APD 217
- 2 Database:CAMP CAMPSQ756
- 3 Database:dbAMP dbAMP_02787
- 4 Database:DRAMP DRAMP03802
- 5 Database:SATPdb satpdb15137
- 6 Database:Uniprot P07469
- 7 Database:DEF DEF267
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000283 From 60 To 93 E-value: 0.000000000000002 Score: 73.2
GICACRRRFCPNSERFSGYCRVNGARYVRCCSRR - 2. L01A002713 From 1 To 34 E-value: 0.0000000000001 Score: 67
GICACRRRFCPNSERFSGYCRVNGARYVRCCSRR - 3. L02A000185 From 1 To 33 E-value: 0.0000000000005 Score: 64.7
ICACRRRFCPNSERFSGYCRVNGARYVRCCSRR - 4. L01A000491 From 1 To 34 E-value: 0.000000000009 Score: 60.8
GICACRRRFCLNFEQFSGYCRVNGARYVRCCSRR - 5. L12A04544| From 1 To 33 E-value: 0.00000000003 Score: 58.9
ICACRRRFCLNFEQFSGYCRVNGARYVRCCSRR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lehrer R.I.,Harwig S.S.L.,Delange R.J.,Brown D.M.,Selsted M.E.,
- Title:Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils.
- Journal:J. Biol. Chem., 1985, 260, 4579-4584 [MEDLINE:85182561]
- [2] Solomon S.,Shimasaki S.,Esch F.,Hu J.,Zhu Q.,
- Title:Isolation and structure of corticostatin peptides from rabbit fetal and adult lung.
- Journal:Proc. Natl. Acad. Sci. U.S.A., 1988, 85, 592-596 [MEDLINE:88124887]
- [3] Solomon S.,Zhu Q.,
- Title:Isolation and mode of action of rabbit corticostatic (antiadrenocorticotropin) peptides.
- Journal:Endocrinology, 1992, 130, 1413-1423 [MEDLINE:92164536]
- [4] Ganz T.,Liu L.,Michaelson D.,Linzmeier R.,
- Title:The structure of neutrophil defensin genes.
- Journal:FEBS Lett., 1993, 321, 267-273 [MEDLINE:93238968]
Comments
- Comments
No comments found on LAMP database