Record in detail


General Info

  • lamp_id:L01A002715
  • Name:CYVA_LEOCM
  • FullName:Cycloviolin-A
  • Source:Leonia cymosa
  • Mass:3235.8 Da
  • Sequence Length:31 aa
  • Isoelectric Point:8.11
  • Activity:Antiviral
  • Sequence
        GVIPCGESCVFIPCISAAIGCSCKNKVCYRN
  • Function:Probably participates in a plant defense mechanism. Has anti-HIV activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A05610|    From 61 To 91 E-value: 0.0000000000007 Score: 64.3
        GVIPCGESCVFIPCISSVLGCSCKNKVCYRN
  • 2. L01A002715    From 1 To 31 E-value: 0.000000000002 Score: 62.8
        GVIPCGESCVFIPCISAAIGCSCKNKVCYRN
  • 3. L12A04244|    From 1 To 31 E-value: 0.00000000001 Score: 60.1
        GVIPCGESCVFIPCISTVIGCSCKNKVCYRN
  • 4. L01A000226    From 1 To 31 E-value: 0.00000000002 Score: 59.3
        GVIPCGESCVFIPCISTLLGCSCKNKVCYRN
  • 5. L12A12205|    From 57 To 87 E-value: 0.00000000003 Score: 59.3
        GTIPCGESCVFIPCLTSAIGCSCKSKVCYKN

Structure

  •   Domains
  •   1  Name:Cyclotide    Interpro Link:IPR005535
  •   2  Name:Cyclotide_bracelet_CS    Interpro Link:IPR012323
  •   3  Name:Cyclotide_subgr    Interpro Link:IPR017307
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Johnson D.G.,Hughes C.B.,Pannell L.K.,Sowder R.C. II,Hallock Y.F.,
  •   Title:Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.
  •   Journal:J. Org. Chem., 2000, 65, 124-128  [PubMed:10813905]

Comments

  •   Comments

    •     No comments found on LAMP database



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