Record in detail


General Info

  • lamp_id:L01A002721
  • Name:CIRC_CHAPA
  • FullName:Circulin-C
  • Source:Chassalia parviflora
  • Mass:3125.7 Da
  • Sequence Length:30 aa
  • Isoelectric Point:8.11
  • Activity:Antiviral
  • Sequence
        CGESCVFIPCITSVAGCSCKSKVCYRNGIP
  • Function:Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002721    From 1 To 30 E-value: 0.000000000007 Score: 61.2
        CGESCVFIPCITSVAGCSCKSKVCYRNGIP
  • 2. L02A001044    From 1 To 30 E-value: 0.0000000002 Score: 56.2
        CGESCVYIPCLTSAVGCSCKSKVCYRNGIP
  • 3. L02A001043    From 1 To 30 E-value: 0.0000000002 Score: 56.2
        CGESCVWIPCLTSAVGCSCKSKVCYRNGIP
  • 4. L02A001046    From 1 To 30 E-value: 0.0000000002 Score: 55.8
        CGESCVYIPCLTSAIGCSCKSKVCYRNGIP
  • 5. L02A001809    From 1 To 30 E-value: 0.0000000003 Score: 55.8
        CGESCVFIPCISSVIGCSCSSKVCYRNGIP

Structure

  •   Domains
  •   1  Name:Cyclotide    Interpro Link:IPR005535
  •   2  Name:Cyclotide_bracelet_CS    Interpro Link:IPR012323
  •   3  Name:Cyclotide_subgr    Interpro Link:IPR017307
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  HIV-1  EC:  50 μg/ml  (15.9964 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Pannell L.K.,Johnson D.G.,Sowder R.C. Jr.,Walton L.K.,Gustafson K.R.,
  •   Title:New circulin macrocyclic polypeptides from Chassalia parvifolia.
  •   Journal:J. Nat. Prod., 2000, 63, 176-178  [PubMed:10691702]

Comments

  •   Comments

    •     No comments found on LAMP database



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