Record in detail
General Info
- lamp_id:L01A002730
- Name:B2DYC_RANDY
- FullName:Brevinin-2DYc
- Source:Rana dybowskii
- Mass:3318 Da
- Sequence Length:33 aa
- Isoelectric Point:9.55
- Activity:Antibacterial, Antifungal
- Sequence
GLFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC - Function:Antimicrobial peptide. A mixture of Brevinin-2DYc/2DYd is active against the Gram-positive bacterium S.aureus (MIC=15 uM) and the Gram-negative bacterium E.coli (MIC=15 uM).
Cross-Linking
- Cross-linking
- 1 Database:APD 566
- 2 Database:APD 608
- 3 Database:CAMP CAMPSQ773
- 4 Database:DBAASP 1478
- 5 Database:dbAMP dbAMP_03308
- 6 Database:DRAMP DRAMP01250
- 7 Database:SATPdb satpdb22855
- 8 Database:Uniprot P0C5X3
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A002730 From 1 To 33 E-value: 0.000000000002 Score: 62.4
GLFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC - 2. L01A000205 From 1 To 33 E-value: 0.000000000004 Score: 62
GIFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC - 3. L01A000204 From 1 To 33 E-value: 0.000000000005 Score: 61.2
GLFDVVKGVLKGAGKNVAGSLLEQLKCKLSGGC - 4. L12A07346| From 39 To 71 E-value: 0.000000000008 Score: 60.8
GLFSVVKGVLKGVGKNVAGSLLEQLKCKISGGC - 5. L13A016275 From 1 To 33 E-value: 0.00000000002 Score: 59.7
GLFSVVKGVLKGVGKNVAGSLLEQLKCKISGGC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 14.931 μg/ml (4.5 μM)
- 2 Target: S. aureus MIC: 29.862 μg/ml (9 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
- Title:Cytolytic peptides belonging to the brevinin-1 and brevinin-2 families isolated from the skin of the Japanese brown frog, Rana dybowskii.
- Journal:Toxicon, 2007, 50, 746-756 [PubMed:17688900]
Comments
- Comments
No comments found on LAMP database