Record in detail


General Info

  • lamp_id:L01A002743
  • Name:PF11_PIG
  • FullName:Prophenin-1
  • Source:Sus scrofa
  • Mass:8681.1 Da
  • Sequence Length:79 aa
  • Isoelectric Point:13.2
  • Activity:Antibacterial
  • Sequence
        AFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFP
  • Function:Exerts antimicrobial activity. It is more effective against Gram-negative bacteria than Gram-positive bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002743    From 1 To 79 E-value: 7e-27 Score: 110
        AFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFP
  • 2. L01A002744    From 1 To 79 E-value: 1e-26 Score: 109
        AFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFP
  • 3. L13A018643    From 1 To 50 E-value: 9e-16 Score: 73.9
        AFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGP
  • 4. L13A018643    From 2 To 50 E-value: 0.0000000000007 Score: 64.3
        FPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGP
  • 5. L13A018643    From 2 To 45 E-value: 0.0000000006 Score: 54.7
        FPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPP

Structure

  •   Domains
  •   1  Name:Cathelicidin    Interpro Link:IPR001894
  •   2  Name:Cathelicidin_CS    Interpro Link:IPR018216
  •   Structures

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lenarcic B.,Renko M.,Kopitar G.,Pungercar J.,Strukelj B.,
  •   Title:Molecular cloning and identification of a novel porcine cathelin-like antibacterial peptide precursor.
  •   Journal:Biol. Chem. Hoppe-Seyler, 1995, 376, 507-510  [MEDLINE:96042752]
  •   [2]  Zhao C.,Aleshina G.M.,Swiderek K.M.,Kokryakov V.N.,Harwig S.S.L.,
  •   Title:Prophenin-1, an exceptionally proline-rich antimicrobial peptide from porcine leukocytes.
  •   Journal:FEBS Lett., 1995, 362, 65-69  [MEDLINE:95212585]

Comments

  •   Comments

  •     No comments found on LAMP database



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