Record in detail
General Info
- lamp_id:L01A002744
- Name:PF12_PIG
- FullName:Prophenin-2
- Source:Sus scrofa
- Mass:8633 Da
- Sequence Length:79 aa
- Isoelectric Point:13.2
- Activity:Antimicrobial
- Sequence
AFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFP - Function:Exerts antimicrobial activity. It is more effective against Gram-negative bacteria than Gram-positive bacteria.
Cross-Linking
- Cross-linking
- 1 Database:APD 690
- 2 Database:CAMP CAMPSQ1494
- 3 Database:dbAMP dbAMP_00188
- 4 Database:DRAMP DRAMP02969
- 5 Database:Uniprot P51525
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A002744 From 1 To 79 E-value: 3e-27 Score: 112
AFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFP - 2. L01A002743 From 1 To 79 E-value: 1e-26 Score: 109
AFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFP - 3. L13A013494 From 1 To 50 E-value: 5e-16 Score: 74.7
AFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGP - 4. L13A013494 From 2 To 50 E-value: 0.0000000000004 Score: 65.1
FPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGP - 5. L13A013494 From 2 To 45 E-value: 0.000000001 Score: 53.5
FPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPP
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lenarcic B.,Renko M.,Kopitar G.,Strukelj B.,Pungercar J.,
- Title:Molecular cloning of a putative homolog of proline/arginine-rich antibacterial peptides from porcine bone marrow.
- Journal:FEBS Lett., 1993, 336, 284-288 [MEDLINE:94085623]
- [2] Lehrer R.I.,Ganz T.,Zhao C.,
- Title:Structures of genes for two cathelin-associated antimicrobial peptides: prophenin-2 and PR-39.
- Journal:FEBS Lett., 1995, 376, 130-134 [MEDLINE:96105365]
Comments
- Comments
No comments found on LAMP database