Record in detail


General Info

  • lamp_id:L01A002811
  • Name:FALX6_LITFA
  • FullName:Preprofallaxidin-6
  • Source:Litoria fallax
  • Mass:1648 Da
  • Sequence Length:16 aa
  • Isoelectric Point:9.53
  • Activity:Antibacterial
  • Sequence
        GLLDLAKHVIGIASKL
  • Function:Fallaxidin-1.3 shows no antibacterial activity against Gram-positive or Gram-negative bacteria. Does not inhibit the formation of NO by neuronal nitric oxide synthase. Has no effect on splenocyte proliferation or smooth muscle contraction.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A06439|    From 47 To 62 E-value: 0.0008 Score: 33.5
        GLLDFAKHVIGIASKL
  • 2. L12A06441|    From 50 To 65 E-value: 0.001 Score: 32.7
        GLLDLAKHVIGIASKL
  • 3. L12A06441|    From 74 To 89 E-value: 0.003 Score: 31.6
        GLLDFAKHVIGIASKL
  • 4. L01A002811    From 1 To 16 E-value: 0.002 Score: 32
        GLLDLAKHVIGIASKL
  • 5. L02A001236    From 1 To 16 E-value: 0.004 Score: 31.2
        GLLDFAKHVIGIASKL

Structure

  •   Domains
  •   1  Name:Brevinin    Interpro Link:IPR004275
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E.faecalis  MIC:  164.8 μg/ml  (100 μM)  
  •   2  Target:  and L.lactis  MIC:  164.8 μg/ml  (100 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Surinya-Johnson K.H.,Musgrave I.F.,Bilusich D.,Bowie J.H.,Jackway R.J.,
  •   Title:The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.
  •   Journal:Rapid Commun. Mass Spectrom., 2008, 22, 3207-3216  [PubMed:18803332]

Comments

  •   Comments

    •     No comments found on LAMP database



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