Record in detail


General Info

  • lamp_id:L01A002821
  • Name:CTHL1_SHEEP
  • FullName:Cathelicidin-1
  • Source:Ovis aries
  • Mass:1548 Da
  • Sequence Length:12 aa
  • Isoelectric Point:12.02
  • Activity:Antibacterial
  • Sequence
        RICRIIFLRVCR
  • Function:Potent microbicidal activity; active against S.aureus and E.coli (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002821    From 1 To 12 E-value: 0.31 Score: 24.6
        RICRIIFLRVCR
  • 2. L01A000485    From 1 To 12 E-value: 7.7 Score: 20
        RLCRIVVIRVCR
  • 3. L11A001063    From 2 To 13 E-value: 9.4 Score: 19.6
        RLCRIVVIRVCR

Structure

  •   Domains
  •   1  Name:Cathelicidin    Interpro Link:IPR001894
  •   2  Name:Cathelicidin_CS    Interpro Link:IPR018216
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Zanetti M.,Scocchi M.,Bagella L.,
  •   Title:cDNA sequences of three sheep myeloid cathelicidins.
  •   Journal:FEBS Lett., 1995, 376, 225-228  [MEDLINE:96105386]
  •   [2]  Broad T.E.,Burkin H.R.,Lambeth M.R.,Huttner K.M.,
  •   Title:Localization and genomic organization of sheep antimicrobial peptides genes.
  •   Journal:Gene, 1998, 206, 85-91  [MEDLINE:98121317]

Comments

  •   Comments

    •     No comments found on LAMP database



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