Record in detail


General Info

  • lamp_id:L01A002822
  • Name:CTHL3_SHEEP
  • FullName:Cathelicidin-3
  • Source:Ovis aries
  • Mass:7464 Da
  • Sequence Length:60 aa
  • Isoelectric Point:13.78
  • Activity:Antimicrobial
  • Sequence
        RRLRPRRPRLPRPRPRPRPRPRSLPLPRPQPRRIPRPILLPWRPPRPIPRPQPQPIPRWL
  • Function:Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002822    From 1 To 60 E-value: 1e-19 Score: 86.7
        RRLRPRRPRLPRPRPRPRPRPRSLPLPRPQPRRIPRPILLPWRPPRPIPRPQPQPIPRWL
  • 2. L01A002741    From 1 To 60 E-value: 7e-19 Score: 84.3
        RRLRPRRPRLPRPRPRPRPRPRSLPLPRPQPRRIPRPILLPWRPPRPIPRPQIQPIPRWL
  • 3. L13A015488    From 1 To 15 E-value: 8.3 Score: 20.8
        RRIPRPILLPWRPPR

Structure

  •   Domains
  •   1  Name:Cathelicidin    Interpro Link:IPR001894
  •   2  Name:Cathelicidin_CS    Interpro Link:IPR018216
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Zanetti M.,Scocchi M.,Bagella L.,
  •   Title:cDNA sequences of three sheep myeloid cathelicidins.
  •   Journal:FEBS Lett., 1995, 376, 225-228  [MEDLINE:96105386]

Comments

  •   Comments

    •     No comments found on LAMP database



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