Record in detail
General Info
- lamp_id:L01A002834
- Name:DEFA_ANOCP
- FullName:Defensin-A
- Source:Anomala cuprea
- Mass:4426.1 Da
- Sequence Length:43 aa
- Isoelectric Point:8.13
- Activity:Antibacterial
- Sequence
VTCDLLSFEAKGFAANHSICAAHCLAIGRKGGSCQNGVCVCRN - Function:Antibacterial protein. Strong activity against the Gram-positive bacteria M.luteus, B.megaterium and S.aureus. Reduced activity against Gram-positive bacterium B.subtilis and weak activity against Gram-negative bacterium X.japonicus. No detectable activity against the Gram-negative bacteria E.asbriae, E.coli, P.aeruginosa and S.marcescens.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ849
- 2 Database:DBAASP 8086
- 3 Database:dbAMP dbAMP_11924
- 4 Database:DRAMP DRAMP02779
- 5 Database:SATPdb satpdb10506
- 6 Database:Uniprot P83669
- 7 Database:AMD DEFA_ANOCP
- 8 Database:AMD DEF_ANOCP
- 9 Database:DEF DEF176
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A002834 From 1 To 43 E-value: 6e-20 Score: 87.8
VTCDLLSFEAKGFAANHSICAAHCLAIGRKGGSCQNGVCVCRN - 2. L01A002934 From 1 To 43 E-value: 4e-19 Score: 85.1
VTCDLLSFEAKGFAANHSICAAHCLVIGRKGGACQNGVCVCRN - 3. L03A000303 From 37 To 79 E-value: 1e-18 Score: 84
LTCDLLSFEAKGFAANHSLCAAHCLAIGRKGGACQNGVCVCRR - 4. L05ADEF136 From 1 To 43 E-value: 2e-18 Score: 82.4
LTCDLLSFEAKGFAANHSLCAAHCLAIGRKGGACQNGVCVCRR - 5. L01A002938 From 1 To 43 E-value: 1e-17 Score: 80.1
VTCDLLSFEAKGFAANHSLCAAHCLAIGRRGGSCERGVCICRR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Yamauchi H.
- Title:Two novel insect defensins from larvae of the cupreous chafer, Anomala cuprea: purification, amino acid sequences and antibacterial activity.
- Journal:Insect Biochem. Mol. Biol., 2001, 32, 75-84 [MEDLINE:21576091]
Comments
- Comments
No comments found on LAMP database