Record in detail


General Info

  • lamp_id:L01A002845
  • Name:DMS6_PHYBI
  • FullName:Dermaseptin-B6
  • Source:Phyllomedusa bicolor
  • Mass:2665.1 Da
  • Sequence Length:24 aa
  • Isoelectric Point:9.45
  • Activity:Antibacterial
  • Sequence
        ALWKDILKNAGKAALNEINQLVNQ
  • Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A06198|    From 46 To 69 E-value: 0.00000002 Score: 49.7
        ALWKDILKNAGKAALNEINQLVNQ
  • 2. L01A002845    From 1 To 24 E-value: 0.00000006 Score: 47.8
        ALWKDILKNAGKAALNEINQLVNQ
  • 3. L13A016729    From 1 To 22 E-value: 0.000001 Score: 43.1
        ALWKDILKNAGKAALNEINQIV
  • 4. L13A010407    From 1 To 22 E-value: 0.000001 Score: 43.1
        ALWKDILKNAGKAALNEINQIV
  • 5. L11A010849    From 1 To 22 E-value: 0.00002 Score: 39.7
        ALWKEVLKNAGKAALNEINNLV

Structure

  •   Domains
  •   1  Name:Brevinin    Interpro Link:IPR004275
  •   2  Name:Dermaseptin_precursor    Interpro Link:IPR016322
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Le Caer J.-P.,Vouille V.,Mester J.,Amiche M.,Charpentier S.,
  •   Title:Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics.
  •   Journal:J. Biol. Chem., 1998, 273, 14690-14697  [MEDLINE:98278974]

Comments

  •   Comments

    •     No comments found on LAMP database



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