Record in detail

lamp_id:L01A002850
Name:PENK_BOVIN
FullName:Proenkephalin-A
Source:Bos taurus
Mass:3353.7 Da
Sequence Length:29 aa
Isoelectric Point:3.95
Activity:Antibacterial
Sequence
FAEPLPSEEEGESYSKEVPEMEKRYGGFM
Function:Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(111-130) and PENK(233-254) increase glutamate release in the striatum. PENK(111-130) decreases GABA concentration in the striatum.

Top similar AMPs on LAMP
1. L03A000063 From 3 To 31 E-value: 0.00000000005 Score: 58.2
FAEPLPSEEEGESYSKEVPEMEKRYGGFM
2. L01A002850 From 1 To 29 E-value: 0.00000000006 Score: 58.2
FAEPLPSEEEGESYSKEVPEMEKRYGGFM
3. L02A000812 From 1 To 29 E-value: 0.0000000005 Score: 55.1
FAEPLPSEEEGESYSKEPPEMEKRYGGFM
4. L11A000647 From 1 To 29 E-value: 0.00004 Score: 38.9
FAEPLPSEEEGEXYXKEVPEMEKRYGGFM
5. L01A000128 From 18 To 29 E-value: 0.039 Score: 28.5
VPEMEKRYGGFM

Reference
[1] Hirose T.,Toyosato M.,Takahashi H.,Furutani Y.,Noda M.,
Title:Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin.
Journal:Nature, 1982, 295, 202-206 [MEDLINE:82125409]
[2] Udenfriend S.,Gage L.P.,Hoffman B.J.,Seeburg P.,Gubler U.,
Title:Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides.
Journal:Nature, 1982, 295, 206-208 [MEDLINE:82125410]
[3] Crea R.,Herbert E.,Comb M.,
Title:Partial characterization of the mRNA that codes for enkephalins in bovine adrenal medulla and human pheochromocytoma.
Journal:Proc. Natl. Acad. Sci. U.S.A., 1982, 79, 360-364 [MEDLINE:82197495]
[4] Poteur L.,Nulans G.,Moniatte M.,Strub J.-M.,Goumon Y.,
Title:The C-terminal bisphosphorylated proenkephalin-A-(209-237)-peptide from adrenal medullary chromaffin granules possesses antibacterial activity.
Journal:Eur. J. Biochem., 1996, 235, 516-525 [MEDLINE:96184524]