Record in detail


General Info

  • lamp_id:L01A002854
  • Name:HEPC_PIG
  • FullName:Hepcidin
  • Source:Sus scrofa
  • Mass:2757.4 Da
  • Sequence Length:25 aa
  • Isoelectric Point:7.98
  • Activity:Antimicrobial
  • Sequence
        DTHFPICIFCCGCCRKAICGMCCKT
  • Function:Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000102    From 58 To 82 E-value: 0.0000000002 Score: 55.8
        DTHFPICIFCCGCCRKAICGMCCKT
  • 2. L01A002854    From 1 To 25 E-value: 0.000000006 Score: 51.2
        DTHFPICIFCCGCCRKAICGMCCKT
  • 3. L12A06325|    From 58 To 82 E-value: 0.000000007 Score: 50.8
        DTHFPICIFCCGCCRKGTCGMCCRT
  • 4. L12A06337|    From 59 To 83 E-value: 0.00000001 Score: 50.4
        DTHFPICMFCCGCCKKARCGMCCKT
  • 5. L12A06335|    From 60 To 84 E-value: 0.00000001 Score: 50.4
        DTHFPICIFCCGCCRQSNCGMCCKT

Structure

  •   Domains
  •   1  Name:Hepcidin    Interpro Link:IPR010500
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference

    •     No references found on LAMP database

Comments

  •   Comments

    •     No comments found on LAMP database



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