Record in detail


General Info

  • lamp_id:L01A002884
  • Name:RK1_RABIT
  • FullName:Corticostatin-related peptide RK-1
  • Source:Oryctolagus cuniculus
  • Mass:3707.3 Da
  • Sequence Length:32 aa
  • Isoelectric Point:7.73
  • Activity:Antibacterial
  • Sequence
        MPCSCKKYCDPWEVIDGSCGLFNSKYICCREK
  • Function:Has antimicrobial activity against E.coli and activates ion channel activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002884    From 1 To 32 E-value: 0.00000000000004 Score: 68.6
        MPCSCKKYCDPWEVIDGSCGLFNSKYICCREK
  • 2. L12A06310|    From 53 To 77 E-value: 1.9 Score: 23.1
        CRKECLENEKPDGSCRL---NFLCCRQR
  • 3. L12A06309|    From 53 To 77 E-value: 2 Score: 23.1
        CRKECLENEKPDGSCRL---NFLCCRQR
  • 4. L12A03264|    From 26 To 50 E-value: 2.1 Score: 23.1
        CRKECLENEKPDGSCRL---NFLCCRQR
  • 5. L12A03263|    From 26 To 50 E-value: 2.1 Score: 23.1
        CRKECLENEKPDGSCRL---NFLCCRQR

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Esch F.,Hu J.,Lembessis P.,MacLeod R.J.,Bateman A.,
  •   Title:The isolation and characterization of a novel corticostatin/defensin-like peptide from the kidney.
  •   Journal:J. Biol. Chem., 1996, 271, 10654-10659  [MEDLINE:96209993]
  •   [2]  Winzor D.J.,Carrington L.E.,Wade J.D.,Dawson N.F.,McManus A.M.,
  •   Title:Three-dimensional structure of RK-1: a novel alpha-defensin peptide.
  •   Journal:Biochemistry, 2000, 39, 15757-15764  [MEDLINE:20573568]

Comments

  •   Comments

  •     No comments found on LAMP database



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