Record in detail


General Info

  • lamp_id:L01A002927
  • Name:DEF1_DERVA
  • FullName:Defensin
  • Source:Dermacentor variabilis
  • Mass:3961.5 Da
  • Sequence Length:36 aa
  • Isoelectric Point:8.88
  • Activity:Antibacterial
  • Sequence
        GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCY
  • Function:Antibacterial activity against Gram-positive and Gram-negative bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000241    From 37 To 72 E-value: 7e-17 Score: 77.8
        GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCY
  • 2. L12A11860|    From 15 To 50 E-value: 1e-16 Score: 76.6
        GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCY
  • 3. L05ADEF234    From 1 To 36 E-value: 4e-16 Score: 75.1
        GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCY
  • 4. L01A002927    From 1 To 36 E-value: 4e-16 Score: 75.1
        GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCY
  • 5. L12A01314|    From 14 To 49 E-value: 5e-16 Score: 74.7
        GFGCPLNQGACHRHCRSIRRRGGYCSGIIKQTCTCY

Structure

  •   Domains
  •   1  Name:Defensin_invertebrate/fungal    Interpro Link:IPR001542
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Hynes W.L.,Sonenshine D.E.,Johns R.,
  •   Title:Identification of a defensin from the hemolymph of the American dog tick, Dermacentor variabilis.
  •   Journal:Insect Biochem. Mol. Biol., 2001, 31, 857-865  [MEDLINE:21332638]
  •   [2]  Hynes W.L.,Ratzlaff R.E.,Sonenshine D.E.,Ceraul S.M.,
  •   Title:An arthropod defensin expressed by the hemocytes of the American dog tick, Dermacentor variabilis (Acari: Ixodidae).
  •   Journal:Insect Biochem. Mol. Biol., 2003, 33, 1099-1103  [PubMed:14563361]

Comments

  •   Comments

    •     No comments found on LAMP database



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