Record in detail


General Info

  • lamp_id:L01A002940
  • Name:DAR12_MOUSE
  • FullName:Alpha-defensin-related sequence 12
  • Source:Mus musculus
  • Mass:2923.6 Da
  • Sequence Length:26 aa
  • Isoelectric Point:8.41
  • Activity:Antimicrobial
  • Sequence
        PPCPSCLSCPWCPRCLRCPMCKCNPK
  • Function:Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats. Unlike cryptdin, the proposed mature peptide region lacks the structural motif characteristic of defensins. It may have microbicidal activities (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000157    From 66 To 91 E-value: 0.0000000003 Score: 55.5
        PPCPSCLSCPWCPRCLRCPMCKCNPK
  • 2. L01A002940    From 1 To 26 E-value: 0.00000002 Score: 49.7
        PPCPSCLSCPWCPRCLRCPMCKCNPK
  • 3. L01A002941    From 1 To 26 E-value: 0.015 Score: 30
        PRCPPCPRCSWCPRCPTCPRCNCNPK
  • 4. L03A000155    From 77 To 92 E-value: 0.09 Score: 27.3
        WCPRCPTCPRCNCNPK
  • 5. L01A002606    From 23 To 38 E-value: 0.19 Score: 26.6
        WCPRCPTCPGCNCNPK

Structure

  •   Domains
  •   1  Name:Alpha-defensin    Interpro Link:IPR016327
  •   2  Name:Defensin_propep    Interpro Link:IPR002366
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Ouellette A.J.,Huttner K.M.,
  •   Title:A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.
  •   Journal:Genomics, 1994, 24, 99-109  [MEDLINE:95203896]

Comments

  •   Comments

    •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: