Record in detail
General Info
- lamp_id:L01A002941
- Name:DFAR7_MOUSE
- FullName:Alpha-defensin-related sequence 7
- Source:Mus musculus
- Mass:2975.5 Da
- Sequence Length:26 aa
- Isoelectric Point:8.61
- Activity:Antimicrobial
- Sequence
PRCPPCPRCSWCPRCPTCPRCNCNPK - Function:Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats. Unlike cryptdin, the proposed mature peptide region lacks the structural motif characteristic of defensins. It may have microbicidal activities.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1579
- 2 Database:dbAMP dbAMP_09989
- 3 Database:DRAMP DRAMP03354
- 4 Database:Uniprot P50715
- 5 Database:DEF DEF122
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000155 From 67 To 92 E-value: 0.0000000004 Score: 55.1
PRCPPCPRCSWCPRCPTCPRCNCNPK - 2. L01A002605 From 13 To 38 E-value: 0.00000002 Score: 49.7
PRCPPCPRCSWCPRCPTCPRCNCNPK - 3. L01A002941 From 1 To 26 E-value: 0.00000005 Score: 48.5
PRCPPCPRCSWCPRCPTCPRCNCNPK - 4. L02A001627 From 22 To 38 E-value: 0.0002 Score: 36.2
SWCPRCPTCPRCNCNPK - 5. L03A000157 From 64 To 91 E-value: 0.0006 Score: 34.7
RCPPCPSCLSCPWCPRCLRCPMCKCNPK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Ouellette A.J.,Huttner K.M.,
- Title:A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.
- Journal:Genomics, 1994, 24, 99-109 [MEDLINE:95203896]
- [2] Andersson M.,Refai E.,Karlsson J.,Putsep K.,Hornef M.W.,
- Title:Increased diversity of intestinal antimicrobial peptides by covalent dimer formation.
- Journal:Nat. Immunol., 2004, 5, 836-843 [PubMed:15235601]
Comments
- Comments
No comments found on LAMP database