Record in detail
General Info
- lamp_id:L01A002942
- Name:DFAR2_MOUSE
- FullName:Alpha-defensin-related sequence 2
- Source:Mus musculus
- Mass:3746.5 Da
- Sequence Length:33 aa
- Isoelectric Point:9.1
- Activity:Antimicrobial
- Sequence
LGWGRRCPQCPRCPSCPSCPRCPRCPRCKCNPK - Function:Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats. Unlike cryptdin, the proposed mature peptide region lacks the structural motif characteristic of defensins. It may have microbicidal activities.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1580
- 2 Database:dbAMP dbAMP_05761
- 3 Database:DRAMP DRAMP03353
- 4 Database:Uniprot P17534
- 5 Database:DEF DEF124
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000154 From 59 To 91 E-value: 0.00000000000003 Score: 68.6
LGWGRRCPQCPRCPSCPSCPRCPRCPRCKCNPK - 2. L02A001625 From 6 To 38 E-value: 0.000000000003 Score: 62.4
LGWGRRCPQCPRCPSCPSCPRCPRCPRCKCNPK - 3. L01A002942 From 1 To 33 E-value: 0.000000000005 Score: 61.2
LGWGRRCPQCPRCPSCPSCPRCPRCPRCKCNPK - 4. L03A000157 From 62 To 91 E-value: 0.000002 Score: 43.1
ARRCPPCPSCLSCPWCPRCLRCPMCKCNPK - 5. L01A002940 From 1 To 26 E-value: 0.0007 Score: 34.3
PPCPSCLSCPWCPRCLRCPMCKCNPK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lauldi J.C.,Ouellette A.J.,
- Title:
- Journal:J. Biol. Chem., 1994, 269, 18702-18702 [MEDLINE:94308115]
- [2] Lauldi J.C.,Ouellette A.J.,
- Title:A novel mouse gene family coding for cationic, cysteine-rich peptides. Regulation in small intestine and cells of myeloid origin.
- Journal:J. Biol. Chem., 1990, 265, 9831-9837 [MEDLINE:90277674]
- [3] Ouellette A.J.,Huttner K.M.,
- Title:A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.
- Journal:Genomics, 1994, 24, 99-109 [MEDLINE:95203896]
Comments
- Comments
No comments found on LAMP database