Record in detail


General Info

  • lamp_id:L01A002977
  • Name:DEF2A_SINAL
  • FullName:Defensin-like protein 2A
  • Source:Sinapis alba
  • Mass:5721.5 Da
  • Sequence Length:51 aa
  • Isoelectric Point:8.6
  • Activity:Antifungal
  • Sequence
        QKLCQRPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC
  • Function:Possesses antifungal activity sensitive to inorganic cations.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002125    From 30 To 80 E-value: 1e-26 Score: 110
        QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
  • 2. L12A06263|    From 30 To 80 E-value: 1e-26 Score: 109
        QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
  • 3. L03A000092    From 30 To 80 E-value: 3e-26 Score: 108
        QKLCQRPSGTWSGVCGNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC
  • 4. L01A002977    From 1 To 51 E-value: 6e-26 Score: 107
        QKLCQRPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC
  • 5. L03A000096    From 30 To 80 E-value: 8e-26 Score: 107
        QKLCERPSGTWSGVCGNSNACKNQCINLEKARHGSCNYVFPAHKCICYFPC

Structure

  •   Domains
  •   1  Name:Gamma-thionin    Interpro Link:IPR008176
  •   2  Name:Knot1    Interpro Link:IPR003614
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Alternaria brassicola  MIC:  4.5 μg/ml  (0.786507 μM)  
  •   2  Target:  Botrytis cinerea  MIC:  3.5 μg/ml  (0.611728 μM)  
  •   3  Target:  Fusarium culmorum  MIC:  2.3 μg/ml  (0.401992 μM)  
  •   4  Target:  Fusarium oxysporum f.sp.lycopersici  MIC:  2.3 μg/ml  (0.401992 μM)  
  •   5  Target:  Pyricularia oryzae  MIC:  0.3 μg/ml  (0.0524338 μM)  
  •   6  Target:  Verticillium dahliae  MIC:  1.2 μg/ml  (0.209735 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Vanderleyden J.,Osborn R.W.,van Leuven F.,Torrekens S.,Terras F.R.G.,
  •   Title:A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
  •   Journal:FEBS Lett., 1993, 316, 233-240  [MEDLINE:93138130]
  •   [2]  Polya G.M.,Condron R.,Neumann G.M.,
  •   Title:Purification and mass spectrometry-based sequencing of yellow mustard (Sinapis alba L.) 6 kDa proteins. Identification as antifungal proteins.
  •   Journal:Int. J. Pept. Protein Res., 1996, 47, 437-446  [MEDLINE:96433791]

Comments

  •   Comments

  •     No comments found on LAMP database



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