Record in detail
General Info
- lamp_id:L01A002989
- Name:CYNT_HALAU
- FullName:Dicynthaurin
- Source:Halocynthia aurantium
- Mass:3105.7 Da
- Sequence Length:30 aa
- Isoelectric Point:10.05
- Activity:Antibacterial
- Sequence
ILQKAVLDCLKAAGSSLSKAAITAIYNKIT - Function:Shows antibacterial activity against both Gram-positive and Gram-negative bacteria. Its antimicrobial activity is optimal at NaCl concentrations below 100 mM, suggesting that the antimicrobial actions of this peptide may take place intracellularly rather than extracellularly. Has no activity against the fungus C.albicans. Has modest hemolytic activity.
Cross-Linking
- Cross-linking
- 1 Database:APD 510
- 2 Database:CAMP CAMPSQ928
- 3 Database:DBAASP 5494
- 4 Database:dbAMP dbAMP_04771
- 5 Database:DRAMP DRAMP02818
- 6 Database:SATPdb satpdb12333
- 7 Database:Uniprot P0C007
- 8 Database:AMD DTH_HALAU
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A002989 From 1 To 30 E-value: 0.00000000005 Score: 58.2
ILQKAVLDCLKAAGSSLSKAAITAIYNKIT - 2. L13A019403 From 1 To 23 E-value: 0.0000008 Score: 44.3
QKAVLDCLKAAGSSLSKAAITAI - 3. L02A001403 From 1 To 25 E-value: 2.9 Score: 22.3
GVLDILKGAGKDLLAHALSKISEKV - 4. L01A003390 From 1 To 25 E-value: 4.2 Score: 21.9
GVLDILKGAAKDLAGHVATKVINKI - 5. L02A001542 From 1 To 21 E-value: 8 Score: 21.2
AVLDFIKAAGKGL----VTNIMEKV
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Hong T.,Kim C.R.,Kim C.H.,Lee Y.S.,Lee I.H.,
- Title:Dicynthaurin: an antimicrobial peptide from hemocytes of the solitary tunicate, Halocynthia aurantium.
- Journal:Biochim. Biophys. Acta, 2001, 1527, 141-148 [MEDLINE:21371813]
Comments
- Comments
No comments found on LAMP database