Record in detail
General Info
- lamp_id:L01A003011
- Name:DEFB3_MOUSE
- FullName:Beta-defensin 3
- Source:Mus musculus
- Mass:4623.6 Da
- Sequence Length:41 aa
- Isoelectric Point:11.05
- Activity:Antibacterial
- Sequence
KKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK - Function:Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1610
- 2 Database:DBAASP 3166
- 3 Database:dbAMP dbAMP_05121
- 4 Database:DRAMP DRAMP03368
- 5 Database:SATPdb satpdb21642
- 6 Database:Uniprot Q9WTL0
- 7 Database:DEF DEF152
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000243 From 23 To 63 E-value: 5e-19 Score: 85.1
KKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK - 2. L01A003011 From 1 To 41 E-value: 3e-18 Score: 82
KKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK - 3. L13A024267 From 1 To 40 E-value: 8e-18 Score: 80.9
KINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK - 4. L03A000249 From 23 To 63 E-value: 0.0000000002 Score: 56.2
QSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK - 5. L01A003488 From 1 To 41 E-value: 0.0000000004 Score: 55.5
QSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Weiner D.J.,Wattler S.,Meegalla R.L.,Wang X.,Bals R.,
- Title:Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs.
- Journal:Infect. Immun., 1999, 67, 3542-3547 [MEDLINE:99307216]
- [2] Vivado A.,Lee S.K.,Schutte B.C.,Wowk S.A.,Jia H.P.,
- Title:A novel murine beta-defensin expressed in tongue, esophagus, and trachea.
- Journal:J. Biol. Chem., 2000, 275, 33314-33320 [MEDLINE:20517883]
- [3]
- Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
- Journal:Genome Res., 2004, 14, 2121-2127 [PubMed:15489334]
Comments
- Comments
No comments found on LAMP database