Record in detail
General Info
- lamp_id:L01A003014
- Name:DFB12_MOUSE
- FullName:Beta-defensin 12
- Source:Mus musculus
- Mass:5805.7 Da
- Sequence Length:51 aa
- Isoelectric Point:8.28
- Activity:Antibacterial
- Sequence
GLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI - Function:Has antibacterial activity (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1613
- 2 Database:dbAMP dbAMP_03269
- 3 Database:DRAMP DRAMP03377
- 4 Database:Uniprot Q8K4N3
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L05ADEF163 From 35 To 85 E-value: 2e-25 Score: 105
GLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI - 2. L01A003014 From 1 To 51 E-value: 1e-24 Score: 103
GLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI - 3. L01A003680 From 1 To 51 E-value: 1e-22 Score: 96.7
GLEYSQSFPGGEFAVCETCRLGRGKCRRTCLDSEKIAGKCKLNFFCCRERI - 4. L12A03268| From 1 To 51 E-value: 3e-21 Score: 92
GLEYSQSFPGGEFSVCETCRLGRGKCRKVCLESERIAGKCKLNFFCCRERI - 5. L12A06581| From 12 To 62 E-value: 7e-19 Score: 84.3
GLEYSQPFPGGEFAACEPCRLGRGKCRKVCTEDEKVVGSCKLNFFCCRRRI
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Tomita T.,Fukuhara S.,Makita R.,Nagase T.,Yamaguchi Y.,
- Title:Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.
- Journal:J. Immunol., 2002, 169, 2516-2523 [MEDLINE:22181517]
- [2] Marquez G.,Martinez-A C.,Albar J.P.,Villares R.,Zaballos A.,
- Title:Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ.
- Journal:J. Biol. Chem., 2004, 279, 12421-12426 [PubMed:14718547]
- [3] Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
- Title:The transcriptional landscape of the mammalian genome.
- Journal:Science, 2005, 309, 1559-1563 [PubMed:16141072]
Comments
- Comments
No comments found on LAMP database