Record in detail

lamp_id:L01A003016
Name:DEFB8_MOUSE
FullName:Beta-defensin 8
Source:Mus musculus
Mass:3842.5 Da
Sequence Length:35 aa
Isoelectric Point:8.89
Activity:Antibacterial
Sequence
NEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK
Function:A synthetic peptide displays antimicrobial activities against S.aureus, P.aeruginosa, E.coli and B.cepacia. The antimicrobial activity against S.aureus, E.coli and B.cepacia is reduced in raised concentration of NaCl, but its action against P.aeruginosa is independent of NaCl concentration.

Top similar AMPs on LAMP
1. L03A000250 From 26 To 60 E-value: 3e-16 Score: 75.5
NEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK
2. L01A003016 From 1 To 35 E-value: 0.000000000000002 Score: 72.8
NEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK
3. L12A09028| From 26 To 60 E-value: 0.00000000000001 Score: 70.1
NDPVTYIRNGGICQYRCIGLRHKIGTCGSPFKCCK
4. L02A001319 From 1 To 34 E-value: 0.0000000000002 Score: 66.2
DPVTYIRNGGICQYRCIGLRHKIGTCGSPFKCCK
5. L03A000253 From 26 To 60 E-value: 0.0000007 Score: 44.3
NSKRACYREGGECLQRCIGLFHKIGTCNFRFKCCK

Reference
[1] Dorin J.R.,Cross S.H.,Kilanowski F.M.,Rolfe M.,Morrison G.M.,
Title:
Journal:Mamm. Genome, 2002, 13, 603-603 [DOI:10.1007/s00335-002-0016-2]
[2] Forssmann W.-G.,Conejo-Garcia J.-R.,Kluever E.,Schweimer K.,Bauer F.,
Title:Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
Journal:Protein Sci., 2001, 10, 2470-2479 [MEDLINE:21571984]
[3] Dorin J.R.,Cross S.H.,Kilanowski F.M.,Rolfe M.,Morrison G.M.,
Title:Identification and characterisation a novel murine beta defensin related gene.
Journal:Mamm. Genome, 2002, 13, 445-451 [MEDLINE:22213784]