Record in detail
General Info
- lamp_id:L01A003018
- Name:DEFB6_MOUSE
- FullName:Beta-defensin 6
- Source:Mus musculus
- Mass:4469.2 Da
- Sequence Length:41 aa
- Isoelectric Point:9.7
- Activity:Antibacterial
- Sequence
QLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK - Function:Has potent antibacterial activity against E.coli (ATCC 25922).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ933
- 2 Database:DBAASP 1957
- 3 Database:dbAMP dbAMP_10168
- 4 Database:DRAMP DRAMP03370
- 5 Database:SATPdb satpdb12314
- 6 Database:Uniprot Q91VD6
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000151 From 23 To 63 E-value: 9e-20 Score: 87
QLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK - 2. L01A003018 From 1 To 41 E-value: 5e-19 Score: 84.7
QLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK - 3. L12A00890| From 1 To 33 E-value: 0.00000000000005 Score: 68.2
CMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK - 4. L01A003488 From 1 To 41 E-value: 0.000000008 Score: 50.8
QSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK - 5. L03A000249 From 23 To 63 E-value: 0.000000009 Score: 50.8
QSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK
Structure
- Domains
- 1 Name:Defensin_beta-typ Interpro Link:IPR001855
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E.coli MIC: 20 μg/ml (4.47507 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Hitomi S.,Tomita T.,Nagase T.,Fukuhara S.,Yamaguchi Y.,
- Title:A novel mouse beta-defensin, mBD-6, predominantly expressed in skeletal muscle.
- Journal:J. Biol. Chem., 2001, 276, 31510-31514 [PubMed:11408484]
Comments
- Comments
No comments found on LAMP database