Record in detail


General Info

  • lamp_id:L01A003018
  • Name:DEFB6_MOUSE
  • FullName:Beta-defensin 6
  • Source:Mus musculus
  • Mass:4469.2 Da
  • Sequence Length:41 aa
  • Isoelectric Point:9.7
  • Activity:Antibacterial
  • Sequence
        QLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK
  • Function:Has potent antibacterial activity against E.coli (ATCC 25922).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000151    From 23 To 63 E-value: 9e-20 Score: 87
        QLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK
  • 2. L01A003018    From 1 To 41 E-value: 5e-19 Score: 84.7
        QLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK
  • 3. L12A00890|    From 1 To 33 E-value: 0.00000000000005 Score: 68.2
        CMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK
  • 4. L01A003488    From 1 To 41 E-value: 0.000000008 Score: 50.8
        QSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK
  • 5. L03A000249    From 23 To 63 E-value: 0.000000009 Score: 50.8
        QSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK

Structure

  •   Domains
  •   1  Name:Defensin_beta-typ    Interpro Link:IPR001855
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E.coli  MIC:  20 μg/ml  (4.47507 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Hitomi S.,Tomita T.,Nagase T.,Fukuhara S.,Yamaguchi Y.,
  •   Title:A novel mouse beta-defensin, mBD-6, predominantly expressed in skeletal muscle.
  •   Journal:J. Biol. Chem., 2001, 276, 31510-31514  [PubMed:11408484]

Comments

  •   Comments

  •     No comments found on LAMP database



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