Record in detail


General Info

  • lamp_id:L01A003023
  • Name:DEFI_ORYRH
  • FullName:Defensin
  • Source:Oryctes rhinoceros
  • Mass:968.2 Da
  • Sequence Length:9 aa
  • Isoelectric Point:9.84
  • Activity:Antibacterial
  • Sequence
        AHCLAIGRK
  • Function:Shows very strong activity against S.aureus.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000303    From 58 To 66 E-value: 1.3 Score: 21.9
        AHCLAIGRK
  • 2. L01A002834    From 22 To 30 E-value: 1.4 Score: 21.9
        AHCLAIGRK
  • 3. L11A010654    From 2 To 10 E-value: 1.5 Score: 21.9
        AHCLAIGRK
  • 4. L01A003023    From 1 To 9 E-value: 1.5 Score: 21.9
        AHCLAIGRK
  • 5. L05ADEF136    From 22 To 30 E-value: 1.6 Score: 21.9
        AHCLAIGRK

Structure

  •   Domains
  •   1  Name:Defensin_insect    Interpro Link:IPR017982
  •   2  Name:Defensin_invertebrate/fungal    Interpro Link:IPR001542
  •   3  Name:Knot1    Interpro Link:IPR003614
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S.�aureus  MIC:  25 μg/ml  (25.8211 μM)  
  •   2  Target:  S.�aureus MRSA  MIC:  50 μg/ml  (51.6422 μM)  
  •   3  Target:  E. coli  MIC:  25 μg/ml  (25.8211 μM)  
  •   4  Target:  P. aeruginosa  MIC:  50 μg/ml  (51.6422 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Yamamoto M.,Nakazawa H.,Saido-Sakanaka H.,Yang J.,Ishibashi J.,
  •   Title:Purification, cDNA cloning and modification of a defensin from the coconut rhinoceros beetle, Oryctes rhinoceros.
  •   Journal:Eur. J. Biochem., 1999, 266, 616-623  [MEDLINE:21060086]

Comments

  •   Comments

  •     No comments found on LAMP database



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