Record in detail

lamp_id:L01A003053
Name:BDEF_TACTR
FullName:Big defensin
Source:Tachypleus tridentatus
Mass:8635.8 Da
Sequence Length:79 aa
Isoelectric Point:9.07
Activity:Antibacterial, Antifungal
Sequence
NPLIPAIYIGATVGPSVWAYLVALVGAAAVTAANIRRASSDNHSCAGNRGWCRSKCFRHEYVDTYYSAVCGRYFCCRSR
Function:Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro.

Top similar AMPs on LAMP
1. L01A003053 From 1 To 79 E-value: 3.99931e-42 Score: 161
NPLIPAIYIGATVGPSVWAYLVALVGAAAVTAANIRRASSDNHSCAGNRGWCRSKCFRHEYVDTYYSAVCGRYFCCRSR
2. L12A09937| From 16 To 89 E-value: 2e-24 Score: 102
IPLVYLGATVSPTVWAWLVGLASAAAVATAGIIRASSDSHSCANNRGWCRSSCFSHEYIDYYNSAVCGRYRCCR
3. L12A09939| From 16 To 89 E-value: 7e-24 Score: 100
IPLVYWGATVSPTVWAWLVGLAGAATVATAGIIRASSDSHSCANNRGWCRSSCFSHEYIDYYNSAVCGRYRCCR
4. L13A021687 From 1 To 50 E-value: 2e-23 Score: 99
NPLIPAIYIGATVGPSVWAYLVALVGAAAVTAANIRRASSDNHSCAGNRG
5. L12A09938| From 16 To 89 E-value: 6e-22 Score: 94.4
IPLVYWGATVSPTVWAWLVGLAGAAAVATAGIIRASSDSHSCANNRGWCRSSCFSHEYIDYYNSAVCGRYRCCR

Reference
[1] Muta T.,Seki N.,Kawasaki S.,Takayenoki Y.,Shigenaga T.,
Title:Separation of large and small granules from horseshoe crab (Tachypleus tridentatus) hemocytes and characterization of their components.
Journal:J. Biochem., 1993, 114, 307-316 [MEDLINE:94110249]
[2] Cho J.,Takayenoki Y.,Shingenaga T.,Kawabata S.,Saito T.,
Title:A novel big defensin identified in horseshoe crab hemocytes: isolation, amino acid sequence, and antibacterial activity.
Journal:J. Biochem., 1995, 117, 1131-1137 [MEDLINE:96172585]
[3] Mizutani A.,Okino N.,Saeki K.,Saito T.,Kawabata S.,
Title:cDNA cloning, tissue distribution, and subcellular localization of horseshoe crab big defensin.
Journal:Biol. Chem., 1997, 378, 289-292 [PubMed:9165083]
[4] Nishimura S.,Osaki T.,Mizuguchi M.,Fujitani N.,Kouno T.,
Title:A novel beta-defensin structure: a potential strategy of big defensin for overcoming resistance by Gram-positive bacteria.
Journal:Biochemistry, 2008, 47, 10611-10619 [PubMed:18785751]