Record in detail
General Info
- lamp_id:L01A003103
- Name:CTHL3_CHICK
- FullName:Cathelicidin-3
- Source:Gallus gallus
- Mass:3351.1 Da
- Sequence Length:29 aa
- Isoelectric Point:12.53
- Activity:Antibacterial
- Sequence
RVKRFWPLVPVAINTVAAGINLYKAIRRK - Function:May bind bacterial lipopolysaccharide (LPS). May have antimicrobial activity and play a role in the innate immune response (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:APD 613
- 2 Database:CAMP CAMPSQ968
- 3 Database:DBAASP 7130
- 4 Database:dbAMP dbAMP_10834
- 5 Database:DRAMP DRAMP03646
- 6 Database:SATPdb satpdb21669
- 7 Database:Uniprot Q2IAL6
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003103 From 1 To 29 E-value: 0.00000000003 Score: 58.9
RVKRFWPLVPVAINTVAAGINLYKAIRRK - 2. L02A001750 From 1 To 29 E-value: 0.00000000007 Score: 57.8
RVRRFWPLVPVAINTVAAGINLYKAIRRK - 3. L12A10487| From 1 To 29 E-value: 0.00000000009 Score: 57.4
RIKRFWPLVPVAINTVAAGINLYKAIKRK - 4. L12A05268| From 1 To 27 E-value: 0.0000000003 Score: 55.8
KRFWPLVPVAINTVAAGINLYKAIRRK - 5. L02A001643 From 1 To 26 E-value: 0.0002 Score: 36.6
RIKRFWPVV---IRTVVAGYNLYRAIKKK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Prakash O.,Fernando S.C.,Bommineni Y.R.,Cai Y.,Xiao Y.,
- Title:Identification and functional characterization of three chicken cathelicidins with potent antimicrobial activity.
- Journal:J. Biol. Chem., 2006, 281, 2858-2867 [PubMed:16326712]
- [2] Kitamura D.,Asano Y.,Benyon L.,Chen C.-I.H.,Goitsuka R.,
- Title:Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway.
- Journal:Proc. Natl. Acad. Sci. U.S.A., 2007, 104, 15063-15068 [PubMed:17827276]
Comments
- Comments
No comments found on LAMP database