Record in detail


General Info

  • lamp_id:L01A003123
  • Name:LANM_STRMU
  • FullName:Lantibiotic mutacin B-Ny266
  • Source:Streptococcus mutans
  • Mass:2424.7 Da
  • Sequence Length:22 aa
  • Isoelectric Point:8.33
  • Activity:Antimicrobial
  • Sequence
        FKSWSFCTPGCAKTGSFNSYCC
  • Function:Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A09385|    From 42 To 63 E-value: 0.00000004 Score: 48.1
        FKSWSLCTPGCARTGSFNSYCC
  • 2. L01A003123    From 1 To 22 E-value: 0.0000001 Score: 47
        FKSWSFCTPGCAKTGSFNSYCC
  • 3. L01A003108    From 1 To 22 E-value: 0.0000003 Score: 45.1
        FKSWSLCTPGCARTGSFNSYCC
  • 4. L02A001002    From 1 To 21 E-value: 0.000001 Score: 43.1
        KSWSLCTPGCARTGSFNSYCC
  • 5. L12A06749|    From 26 To 47 E-value: 0.00001 Score: 40
        ITSHSLCTPGCAKTGSFNSFCC

Structure

  •   Domains
  •   1  Name:Gallidermin    Interpro Link:IPR006078
  •   2  Name:Lan    Interpro Link:IPR006079
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lavoie M.C.,Lapointe G.,Lacroix C.,Mota-Meira M.,
  •   Title:Purification and structure of mutacin B-Ny266: a new lantibiotic produced by Streptococcus mutans.
  •   Journal:FEBS Lett., 1997, 410, 275-279  [MEDLINE:97379322]

Comments

  •   Comments

    •     No comments found on LAMP database



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