Record in detail


General Info

  • lamp_id:L01A003155
  • Name:HEPC_CANFA
  • FullName:Hepcidin
  • Source:Canis familiaris
  • Mass:6532.6 Da
  • Sequence Length:59 aa
  • Isoelectric Point:8.61
  • Activity:Antimicrobial
  • Sequence
        PHQTGQLTDLRAQDTAGAEAGLQPTLQLRRLRRRDTHFPICIFCCGCCKTPKCGLCCKT
  • Function:Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003155    From 1 To 59 E-value: 2e-29 Score: 119
        PHQTGQLTDLRAQDTAGAEAGLQPTLQLRRLRRRDTHFPICIFCCGCCKTPKCGLCCKT
  • 2. L01A002642    From 1 To 59 E-value: 5e-29 Score: 117
        PHQTGQLTDLRAQDTAGAEAGLQPTLQLRRLRRRDTHFPICIFCCGCCKTPKCGFCCKT
  • 3. L01A002633    From 1 To 59 E-value: 1e-28 Score: 116
        PHQTGQLTDLRAQDTAGAEAGLQPTLQLRRLRRRDTHFPICIFCCGCCKTPKCGLCCIT
  • 4. L12A06337|    From 28 To 83 E-value: 5e-21 Score: 91.3
        QETGQLTDLQPQDTAAAEAGLKPVLQ--RLRRRDTHFPICMFCCGCCKKARCGMCCKT
  • 5. L12A06343|    From 27 To 82 E-value: 1e-19 Score: 86.7
        HQTTQLADLQTQDTAGATAGLMPGLQRRR--RRDTHFPICIFCCGCCYPSKCGICCKT

Structure

  •   Domains
  •   1  Name:Hepcidin    Interpro Link:IPR010500
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference

    •     No references found on LAMP database

Comments

  •   Comments

    •     No comments found on LAMP database



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