Record in detail


General Info

  • lamp_id:L01A003276
  • Name:DMS3_PHYAZ
  • FullName:Dermaseptin-H3
  • Source:Phyllomedusa azurea
  • Mass:1983.3 Da
  • Sequence Length:21 aa
  • Isoelectric Point:10.8
  • Activity:Antibacterial
  • Sequence
        GLWSTIKNVAAAAGKAALGAL
  • Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003276    From 1 To 21 E-value: 0.00002 Score: 39.7
        GLWSTIKNVAAAAGKAALGAL
  • 2. L12A05358|    From 41 To 65 E-value: 0.005 Score: 31.2
        GLWSTIKNVGKEAAIAAGKAVLGSL
  • 3. L02A001352    From 1 To 25 E-value: 0.011 Score: 30
        GLWSTIKNVGKEAAIAAGKAVLGSL
  • 4. L01A003280    From 1 To 25 E-value: 0.012 Score: 30
        GLWSTIKNVGKEAAIAAGKAVLGSL
  • 5. L03A000087    From 47 To 66 E-value: 0.038 Score: 28.5
        LWSKIKEMAATAGKAALNAV

Structure

  •   Domains
  •   1  Name:Brevinin    Interpro Link:IPR004275
  •   2  Name:Dermaseptin    Interpro Link:IPR022731
  •   3  Name:Dermaseptin_precursor    Interpro Link:IPR016322
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  McClean S.,Shaw C.,Orr D.F.,Bjourson A.J.,Thompson A.H.,
  •   Title:A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea.
  •   Journal:Peptides, 2007, 28, 1331-1343  [PubMed:17553595]

Comments

  •   Comments

    •     No comments found on LAMP database



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