Record in detail
General Info
- lamp_id:L01A003302
- Name:BR2PE_RANPC
- FullName:Brevinin-2PTe
- Source:Rana picturata
- Mass:3405 Da
- Sequence Length:33 aa
- Isoelectric Point:9.55
- Activity:Antibacterial
- Sequence
GFLDSFKNAMIGVAKSVGKTALSTLACKIDKSC - Function:Has antibacterial activity against the Gram-positive bacterium S.aureus ATCC 25923 (MIC=36uM) and the Gram-negative bacterium E.coli ATCC 25726 (MIC=18uM).
Cross-Linking
- Cross-linking
- 1 Database:APD 1431
- 2 Database:CAMP CAMPSQ1070
- 3 Database:DBAASP 2213
- 4 Database:dbAMP dbAMP_02627
- 5 Database:DRAMP DRAMP01959
- 6 Database:SATPdb satpdb25985
- 7 Database:Uniprot P0C8T7
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003302 From 1 To 33 E-value: 0.0000000000002 Score: 66.2
GFLDSFKNAMIGVAKSVGKTALSTLACKIDKSC - 2. L01A003303 From 1 To 33 E-value: 0.000000000003 Score: 62.4
GFLDSFKNAMIGVAKSAGKTALNTLACKIDKTC - 3. L01A003380 From 1 To 33 E-value: 0.0000000001 Score: 56.6
GLLDSFKNAMIGIAKSAGKTALNKIACKIDKTC - 4. L01A003381 From 1 To 33 E-value: 0.00000002 Score: 49.7
GFKGAFKNVMFGIAKSAGKSALNALACKIDKSC - 5. L12A07302| From 44 To 76 E-value: 0.000004 Score: 42
GLLDTLKNVAIGVAKGAGVGVLNALSCKLDKSC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: S.aureus ATCC 25923 MIC: 122.58 μg/ml (36 μM)
- 2 Target: E. coli MIC: 61.29 μg/ml (18 μM)
- 3 Target: S. aureus MIC: 122.58 μg/ml (36 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
- Title:Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae).
- Journal:Toxicon, 2008, 52, 465-473 [PubMed:18621071]
Comments
- Comments
No comments found on LAMP database