Record in detail
General Info
- lamp_id:L01A003305
- Name:BR2HA_RANHO
- FullName:Brevinin-2HSa
- Source:Rana hosii
- Mass:3332.9 Da
- Sequence Length:33 aa
- Isoelectric Point:9.6
- Activity:Antibacterial
- Sequence
GLLDSLKNLAINAAKGAGQSVLNTLSCKLSKTC - Function:Has antibacterial activity against the Gram-positive bacterium S.aureus ATCC 25923 (MIC=18uM) and the Gram-negative bacterium E.coli ATCC 25726 (MIC=36uM).
Cross-Linking
- Cross-linking
- 1 Database:APD 1421
- 2 Database:CAMP CAMPSQ1073
- 3 Database:DBAASP 2214
- 4 Database:dbAMP dbAMP_03512
- 5 Database:DRAMP DRAMP01953
- 6 Database:SATPdb satpdb18394
- 7 Database:Uniprot P0C8S9
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003305 From 1 To 33 E-value: 0.000000000001 Score: 63.5
GLLDSLKNLAINAAKGAGQSVLNTLSCKLSKTC - 2. L01A003304 From 1 To 33 E-value: 0.000000000003 Score: 62.4
GLLDTLKNMAINAAKGAGQSVLNTLSCKLSKTC - 3. L01A003973 From 1 To 33 E-value: 0.00000000008 Score: 57.4
GLLDTLKNMAINAAKGAGVSVLNALSCKLSKTC - 4. L12A07133| From 45 To 76 E-value: 0.00000000008 Score: 57.4
FLDTLKNLAISAAKGAGQSVLSTLSCKLSKTC - 5. L01A003966 From 1 To 33 E-value: 0.0000000001 Score: 57
GLLDTLKNMAINAAKDAGVSVLNTLSCKLSKTC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 119.984 μg/ml (36 μM)
- 2 Target: S. aureus MIC: 59.9922 μg/ml (18 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
- Title:Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae).
- Journal:Toxicon, 2008, 52, 465-473 [PubMed:18621071]
Comments
- Comments
No comments found on LAMP database