Record in detail


General Info

  • lamp_id:L01A003308
  • Name:M3H14_BOMMX
  • FullName:Maximins 3/H14
  • Source:Bombina maxima
  • Mass:1986.5 Da
  • Sequence Length:20 aa
  • Isoelectric Point:9.53
  • Activity:Antibacterial, Antifungal
  • Sequence
        ILGPVLGLVGEPLGGLIKKI
  • Function:Maximin-3 shows antibacterial activity against both Gram-positive and Gram-negative bacteria. It shows also antimicrobial activity against the fungus C.albicans, but not against A.flavus nor P.uticale. It has little hemolytic activity. It possess a significant cytotoxicity against tumor cell lines. It possess a significant anti-HIV activity. It shows high spermicidal activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003308    From 1 To 20 E-value: 0.0001 Score: 36.6
        ILGPVLGLVGEPLGGLIKKI
  • 2. L13A023880    From 1 To 20 E-value: 0.0004 Score: 35
        ILGPVLGLVGNPLGGLIKKI
  • 3. L01A000285    From 1 To 20 E-value: 0.002 Score: 32.7
        ILGPVLGLVGNALGGLIKKI
  • 4. L01A002470    From 1 To 20 E-value: 0.002 Score: 32.7
        ILGPVLGLVGSALGGLIKKI
  • 5. L13A024696    From 1 To 20 E-value: 0.002 Score: 32.7
        ILGPVLGLVGNTLGGLIKKI

Structure

  •   Domains
  •   1  Name:Bombinin    Interpro Link:IPR007962
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Liu H.,Liu G.-J.,Shen J.-H.,Zheng Y.-T.,Lai R.,
  •   Title:Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
  •   Journal:Peptides, 2002, 23, 427-435  [MEDLINE:21826911]
  •   [2]  Zhang Y.,Li S.,Lai R.,Li Y.,Lee W.-H.,
  •   Title:Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
  •   Journal:Eur. J. Immunol., 2005, 35, 1220-1229  [PubMed:15770703]

Comments

  •   Comments

    •     No comments found on LAMP database



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