Record in detail

General Info

lamp_id:L01A003338
Name:M8H7_BOMMX
FullName:Maximins 8/H7
Source:Bombina maxima
Mass:1975.5 Da
Sequence Length:20 aa
Isoelectric Point:10.8
Activity:Antibacterial, Antifungal
Sequence
ILGPVIKTIGGVIGGLLKNL
Function:Maximin-8 shows antimicrobial activity against bacteria and against the fungus C.albicans. It has little hemolytic activity (By similarity).

Cross-Linking

Cross-linking
1 Database:APD 1744
2 Database:CAMP CAMPSQ1780
3 Database:DBAASP 4161
4 Database:dbAMP dbAMP_04714
5 Database:DRAMP DRAMP01129
6 Database:SATPdb satpdb10308
7 Database:Uniprot Q58T56

Top similar AMPs

Top similar AMPs on LAMP
1. L01A003338 From 1 To 20 E-value: 0.0001 Score: 37
ILGPVIKTIGGVIGGLLKNL
2. L01A003335 From 1 To 20 E-value: 0.0002 Score: 35.8
ILGPVIKTIGGVLGGLLKNL
3. L01A000280 From 1 To 20 E-value: 0.0006 Score: 34.3
ILGPVISTIGGVLGGLLKNL
4. L13A022149 From 1 To 19 E-value: 0.001 Score: 33.1
ILGPVISTIGGVLGGLLKN
5. L13A014180 From 1 To 20 E-value: 0.002 Score: 32.7
ILGPVISTIGNVLGGLLKNL

Structure

Domains
1 Name:Bombinin Interpro Link:IPR007962

Structures

Activity

Antibacterial Activities
1 Target: S. aureus MIC: 9.40338 μg/ml (4.76 μM)

Toxicity

Toxicity

Reference

Reference
[1] Zhang Y.,Li S.,Lai R.,Li Y.,Lee W.-H.,
Title:Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
Journal:Eur. J. Immunol., 2005, 35, 1220-1229 [PubMed:15770703]

Comments

Comments