Record in detail
General Info
- lamp_id:L01A003370
- Name:ES1HA_RANHO
- FullName:Esculentin-1HSa
- Source:Rana hosii
- Mass:4812.7 Da
- Sequence Length:46 aa
- Isoelectric Point:10.34
- Activity:Antibacterial
- Sequence
GIFSKFGGKAIKNLFIKGAKNIGKEVGMDVIRTGIDVAGCKIKGEC - Function:Has antibacterial activity against the Gram-positive bacterium S.aureus ATCC 25923 (MIC=12uM) and the Gram-negative bacterium E.coli ATCC 25726 (MIC=12uM).
Cross-Linking
- Cross-linking
- 1 Database:APD 1419
- 2 Database:CAMP CAMPSQ1077
- 3 Database:DBAASP 2215
- 4 Database:dbAMP dbAMP_02838
- 5 Database:DRAMP DRAMP01477
- 6 Database:SATPdb satpdb10976
- 7 Database:Uniprot P0C8T8
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003370 From 1 To 46 E-value: 5e-20 Score: 88.2
GIFSKFGGKAIKNLFIKGAKNIGKEVGMDVIRTGIDVAGCKIKGEC - 2. L12A06987| From 39 To 84 E-value: 1e-18 Score: 83.6
GIFSKISGKAIKNLFIKGAKNVGKEVGMDVVRTGIDVVGCKIKGEC - 3. L02A001861 From 1 To 46 E-value: 4e-18 Score: 81.6
GIFSKISGKAIKNLFIKGAKNVGKEVGMDVVRTGIDVVGCKIKGEC - 4. L12A06983| From 39 To 84 E-value: 6e-18 Score: 80.9
GIFSKFAGKGIKNLLVKGVKNIGKEVGMDVIRTGIDIAGCKIKGEC - 5. L102925000 From 1 To 46 E-value: 7e-18 Score: 80.9
GIFSKISGKAIKNLFIKGAKNVGKEVGMDVVRTGMDVVGCKIKGEC
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: S.aureus ATCC 25923 MIC: 57.75 μg/ml (11.9995 μM)
- 2 Target: E.coli ATCC 25726 MIC: 57.75 μg/ml (11.9995 μM)
- 3 Target: E. coli MIC: 57.7524 μg/ml (12 μM)
- 4 Target: S. aureus MIC: 57.7524 μg/ml (12 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
- Title:Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae).
- Journal:Toxicon, 2008, 52, 465-473 [PubMed:18621071]
Comments
- Comments
No comments found on LAMP database